PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26827254-7	2016	RESULTS: In J82, RT4, TCCsup and 5637 UC cells, mel-flufen amplified the intracellular loading of melphalan in part via aminopeptidase N (ANPEP), resulting in increased cytotoxicity compared to melphalan alone.	Melphalan	98-107	alanyl aminopeptidase, membrane	Homo sapiens	120-136	
26827254-7	2016	RESULTS: In J82, RT4, TCCsup and 5637 UC cells, mel-flufen amplified the intracellular loading of melphalan in part via aminopeptidase N (ANPEP), resulting in increased cytotoxicity compared to melphalan alone.	Melphalan	98-107	alanyl aminopeptidase, membrane	Homo sapiens	138-143	
26827254-7	2016	RESULTS: In J82, RT4, TCCsup and 5637 UC cells, mel-flufen amplified the intracellular loading of melphalan in part via aminopeptidase N (ANPEP), resulting in increased cytotoxicity compared to melphalan alone.	Melphalan	194-203	alanyl aminopeptidase, membrane	Homo sapiens	138-143	
23584492-7	2013	Mechanistic studies show that siRNA knockdown of aminopeptidase N, a key enzyme mediating intracellular conversion of mel-flufen to melphalan, attenuates anti-multiple myeloma activity of mel-flufen.	Melphalan	132-141	alanyl aminopeptidase, membrane	Homo sapiens	49-65	
20067771-0	2010	The alkylating prodrug J1 can be activated by aminopeptidase N, leading to a possible target directed release of melphalan.	Melphalan	113-122	alanyl aminopeptidase, membrane	Homo sapiens	46-62	
32774473-2	2020	This study aims to investigate the role of aminopeptidase N (ANPEP) in HGOS progression and its targeting with a novel lipophilic peptidase-enhanced cytotoxic compound melphalan flufenamide (melflufen) in HGOS.	Melphalan	168-177	alanyl aminopeptidase, membrane	Homo sapiens	61-66