PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24706190-6	2014	Consistent with these results, caspase-3 was activated more strongly by melphalan than by other agents in combination with bortezomib.	Melphalan	72-81	caspase 3	Homo sapiens	31-40	
21241278-5	2011	Siltuximab with melphalan enhanced activation of caspase-8, caspase-9, and the downstream effector caspase-3 compared with either of the single agents.	Melphalan	16-25	caspase 3	Homo sapiens	99-108	
35163680-6	2022	Melphalan derivatives were evaluated for cytotoxicity (resazurin viability assay), genotoxicity (alkaline comet assay), and their ability to induce apoptosis (Hoechst33342/propidium iodide double staining method; phosphatidylserine translocation; and caspase 3/7, 8, and 9 activity measurements).	Melphalan	0-9	caspase 3	Homo sapiens	251-262