PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29057477-5	2018	Moreover, combination treatment with MIP-1alpha neutralizing antibody and melphalan or bortezomib inhibited extracellular signal regulated kinase 1/2 (ERK1/2), Akt, and mammalian target of rapamycin (mTOR) activation, Bcl-2, Bcl-xL, and Survivin expression, and upregulated the expression of Bim and cleaved Poly (ADP-ribose) polymerase (PARP).	Melphalan	74-83	poly(ADP-ribose) polymerase 1	Homo sapiens	308-336	
6090366-0	1984	Enhancement of melphalan cytotoxicity in vivo and in vitro by inhibitors of poly (ADP-ribose) polymerase.	Melphalan	15-24	poly(ADP-ribose) polymerase 1	Homo sapiens	76-104	
6090366-1	1984	In these preliminary experiments, we have found enhanced cell killing by the bifunctional alkylating agent L-phenylalanine mustard (L-PAM) in the presence of inhibitors of poly (ADP-ribose) polymerase (ADPRP) in vitro.	Melphalan	132-137	poly(ADP-ribose) polymerase 1	Homo sapiens	172-200	
32194286-0	2020	PARP inhibition synergizes with melphalan but does not reverse resistance completely.	Melphalan	32-41	poly(ADP-ribose) polymerase 1	Homo sapiens	0-4	
29057477-5	2018	Moreover, combination treatment with MIP-1alpha neutralizing antibody and melphalan or bortezomib inhibited extracellular signal regulated kinase 1/2 (ERK1/2), Akt, and mammalian target of rapamycin (mTOR) activation, Bcl-2, Bcl-xL, and Survivin expression, and upregulated the expression of Bim and cleaved Poly (ADP-ribose) polymerase (PARP).	Melphalan	74-83	poly(ADP-ribose) polymerase 1	Homo sapiens	338-342	
28394191-0	2017	The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells.	Melphalan	92-101	poly(ADP-ribose) polymerase 1	Homo sapiens	4-8	
23613505-5	2013	These transfected cells, together with control RPMI-8226 cells, were treated with 20 micromol/l melphalan for 24 h. Knockdown of DEPTOR exacerbated melphalan-induced growth inhibition and apoptosis, increased levels of cleaved caspase-3 and cleaved PARP, and reduced levels of phosphor-AKT.	Melphalan	148-157	poly(ADP-ribose) polymerase 1	Homo sapiens	249-253