PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1713580-4	1991	Acute treatment with phorbol esters resulted in increased collagen IV, tPA, PAI-1, and interstitial collagenase mRNAs; the type IV collagenase mRNA levels were instead suppressed to 50% of control.	Phorbol Esters	21-35	chromosome 20 open reading frame 181	Homo sapiens	71-74	
1713580-6	1991	Intracellular elevation of cAMP led to over-expression of fibronectin and type IV collagenase and potentiated the effects of phorbol esters on collagen IV, tPA, and interstitial collagenase expression.	Phorbol Esters	125-139	chromosome 20 open reading frame 181	Homo sapiens	156-159	
1701436-3	1990	Both phorbol esters and cAMP elevating compounds have been shown to modulate PAI-1 and tPA expression in endothelial cell culture.	Phorbol Esters	5-19	chromosome 20 open reading frame 181	Homo sapiens	87-90	
2117475-0	1990	Regulation of endothelial tissue plasminogen activator and plasminogen activator inhibitor type 1 synthesis by diacylglycerol, phorbol ester, and thrombin.	Phorbol Esters	127-140	chromosome 20 open reading frame 181	Homo sapiens	26-54	
2460455-0	1988	Cyclic AMP potentiates phorbol ester stimulation of tissue plasminogen activator release and inhibits secretion of plasminogen activator inhibitor-1 from human endothelial cells.	Phorbol Esters	23-36	chromosome 20 open reading frame 181	Homo sapiens	52-80	
2506174-2	1989	Tumor-promoting phorbol esters stimulate tissue plasminogen activator (tPA) release from human endothelial cells, and simultaneous elevation of cyclic AMP potentiates this response 5-fold (Santell, L., and Levin, E. G. (1988) J. Biol.	Phorbol Esters	16-30	chromosome 20 open reading frame 181	Homo sapiens	41-69	
2506174-2	1989	Tumor-promoting phorbol esters stimulate tissue plasminogen activator (tPA) release from human endothelial cells, and simultaneous elevation of cyclic AMP potentiates this response 5-fold (Santell, L., and Levin, E. G. (1988) J. Biol.	Phorbol Esters	16-30	chromosome 20 open reading frame 181	Homo sapiens	71-74