PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12844482-0	2003	Curcumin inhibits phorbol ester-induced expression of cyclooxygenase-2 in mouse skin through suppression of extracellular signal-regulated kinase activity and NF-kappaB activation.	Phorbol Esters	18-31	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	159-168	
18084005-0	2008	Phorbol ester up-regulates phospholipase D1 but not phospholipase D2 expression through a PKC/Ras/ERK/NFkappaB-dependent pathway and enhances matrix metalloproteinase-9 secretion in colon cancer cells.	Phorbol Esters	0-13	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	102-110	
17404063-0	2007	Epigallocatechin gallate inhibits phorbol ester-induced activation of NF-kappa B and CREB in mouse skin: role of p38 MAPK.	Phorbol Esters	34-47	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	70-80	
16474181-0	2006	Resveratrol inhibits phorbol ester-induced expression of COX-2 and activation of NF-kappaB in mouse skin by blocking IkappaB kinase activity.	Phorbol Esters	21-34	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	81-90	
15735738-0	2005	[6]-Gingerol inhibits COX-2 expression by blocking the activation of p38 MAP kinase and NF-kappaB in phorbol ester-stimulated mouse skin.	Phorbol Esters	101-114	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	88-97	
16950795-0	2007	cis-9,trans-11-conjugated linoleic acid down-regulates phorbol ester-induced NF-kappaB activation and subsequent COX-2 expression in hairless mouse skin by targeting IkappaB kinase and PI3K-Akt.	Phorbol Esters	55-68	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	77-86	
12962141-0	2003	Phorbol esters induce translocation of the nPKC p105 to membrane in mussel hemocytes.	Phorbol Esters	0-14	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	48-52	
12929133-0	2003	Synergistic expression of inducible nitric oxide synthase by phorbol ester and interferon-gamma is mediated through NF-kappaB and ERK in microglial cells.	Phorbol Esters	61-74	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	116-125	
1730783-0	1992	Regulation of NF-kappa B activity in murine macrophages: effect of bacterial lipopolysaccharide and phorbol ester.	Phorbol Esters	100-113	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	14-24	
11387339-6	2001	A dominant negative Bimp1 mutant inhibits NF-kappaB activation by anti-CD3 ligation, phorbol ester, and protein kinase C expression.	Phorbol Esters	85-98	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	42-51	
9466823-5	1998	Furthermore, PKC down-regulation (through preincubation with phorbol esters) also affected only baseline NF-kappa B DNA binding but not H2O2-stimulated NF-kappa B activation.	Phorbol Esters	61-75	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	105-115	
12086399-0	2002	Effects of yakuchinone A and yakuchinone B on the phorbol ester-induced expression of COX-2 and iNOS and activation of NF-kappaB in mouse skin.	Phorbol Esters	50-63	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	119-128	
11179825-0	2001	Capsaicin suppresses phorbol ester-induced activation of NF-kappaB/Rel and AP-1 transcription factors in mouse epidermis.	Phorbol Esters	21-34	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	57-66	
11179825-2	2001	In the present study, topical application of capsaicin onto dorsal skin of female ICR mice strongly suppressed phorbol ester-stimulated activation of NF-kappaB via blockade of IkappaB-alpha degradation with subsequent inhibition of nuclear translocation of the functionally active NF-kappaB subunit, p65.	Phorbol Esters	111-124	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	150-159	
11179825-2	2001	In the present study, topical application of capsaicin onto dorsal skin of female ICR mice strongly suppressed phorbol ester-stimulated activation of NF-kappaB via blockade of IkappaB-alpha degradation with subsequent inhibition of nuclear translocation of the functionally active NF-kappaB subunit, p65.	Phorbol Esters	111-124	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	281-290	
9927206-0	1999	Taxol selectively blocks microtubule dependent NF-kappaB activation by phorbol ester via inhibition of IkappaBalpha phosphorylation and degradation.	Phorbol Esters	71-84	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	47-56	
9430659-3	1998	Here we show that SLs prevented the activation of NF-kappa B by different stimuli such as phorbol esters, tumor necrosis factor-alpha, ligation of the T-cell receptor, and hydrogen peroxide in various cell types.	Phorbol Esters	90-104	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	50-60	
3145412-0	1988	The NF-kappa B-binding site mediates phorbol ester-inducible transcription in nonlymphoid cells.	Phorbol Esters	37-50	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	4-14	
2105908-6	1990	Although NF-kappa B cannot be activated by LPS, it can be activated by treatment with phorbol ester (PMA).	Phorbol Esters	86-99	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	9-19	
1675604-6	1991	This mutant also functions in vivo as a trans-acting dominant negative regulator: the transcriptional inducibility of the HIV long terminal repeat (which contains two potential NF-kappa B binding sites) by phorbol ester (PMA) is inhibited when it is co-transfected into CD4+ T cells with the delta SP mutant.	Phorbol Esters	206-219	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	177-187	
2059661-0	1991	Evidence that interleukin-1 and phorbol esters activate NF-kappa B by different pathways: role of protein kinase C. Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor that affects expression of many genes, including immunoglobulin kappa (kappa), the interleukin-2 receptor alpha chain, and two genes in HIV-1.	Phorbol Esters	32-46	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	56-66	
2059661-0	1991	Evidence that interleukin-1 and phorbol esters activate NF-kappa B by different pathways: role of protein kinase C. Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor that affects expression of many genes, including immunoglobulin kappa (kappa), the interleukin-2 receptor alpha chain, and two genes in HIV-1.	Phorbol Esters	32-46	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	140-150	
2530301-3	1989	Transfection analysis shows that a 60-bp fragment encompassing this site is preferentially active in T cells stimulated with phorbol esters or the HTLV-1 tax gene product compared with a B cell line that constitutively expresses NF-kappa B.	Phorbol Esters	125-139	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	229-239	
3129195-3	1988	By using a variety of protocols involving the dissociating agents sodium desoxycholate and formamide, as much cytosolic NF-kappa B can be found in the fraction from unstimulated 70Z/3 pre-B cells as is found in the nuclear extract from phorbol ester-activated cells.	Phorbol Esters	236-249	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	120-130	
23911786-0	2013	Thymoquinone inhibits phorbol ester-induced activation of NF-kappaB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo.	Phorbol Esters	22-35	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	58-67