PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1652433-12 1991 While the mechanism of TGF beta action is not clear, A-II probably is acting through protein kinase C. Indeed the protein kinase C activating phorbol ester, TPA, mimicked the inhibitory effects of A-II on 3 beta HSD and P450(17 alpha). Phorbol Esters 142-155 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase Bos taurus 205-215