PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 17161819-0 2007 Anti-inflammatory effects of short chain fatty acids in IFN-gamma-stimulated RAW 264.7 murine macrophage cells: involvement of NF-kappaB and ERK signaling pathways. Fatty Acids, Volatile 29-52 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 127-136 22669487-0 2012 Short-chain fatty acids suppress lipopolysaccharide-induced production of nitric oxide and proinflammatory cytokines through inhibition of NF-kappaB pathway in RAW264.7 cells. Fatty Acids, Volatile 0-23 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 139-148 32831998-0 2020 Short-Chain Fatty Acids Ameliorate Diabetic Nephropathy via GPR43-Mediated Inhibition of Oxidative Stress and NF-kappaB Signaling. Fatty Acids, Volatile 0-23 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 110-119 32831998-6 2020 We found that exogenous SCFAs, especially butyrate, improved hyperglycemia and insulin resistance; prevented the formation of proteinuria and an increase in serum creatinine, urea nitrogen, and cystatin C; inhibited mesangial matrix accumulation and renal fibrosis; and blocked NF-kappaB activation in mice. Fatty Acids, Volatile 24-29 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 278-287 32831998-7 2020 SCFAs also inhibited high glucose-induced oxidative stress and NF-kappaB activation and enhanced the interaction between beta-arrestin-2 and I-kappaBalpha in GMCs. Fatty Acids, Volatile 0-5 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 63-72 32831998-9 2020 These results support the conclusion that SCFAs, especially butyrate, partially improve T2D-induced kidney injury via GPR43-mediated inhibition of oxidative stress and NF-kappaB signaling, suggesting SCFAs may be potential therapeutic agents in the prevention and treatment of DN. Fatty Acids, Volatile 42-47 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 168-177