PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33085904-8 2021 SCFAs, products of microbial metabolism of complex carbohydrates of breastmilk oligosaccharides, have been found with this study to induce an anti-IL-1beta response that is associated with an upregulation of tight junctions and mucus genes in epithelial cells (H4 cells). Fatty Acids, Volatile 0-5 interleukin 1 alpha Homo sapiens 147-155 34208638-5 2021 SCFA down-attenuated host pro-inflammatory IL-1beta, IL-6, and TNFalpha response predominantly through the TLR4 pathway, whereas MCFA augmented inflammation through TLR2. Fatty Acids, Volatile 0-4 interleukin 1 alpha Homo sapiens 43-51 33851870-0 2021 Lung Immune Tone via Gut-Lung Axis: Gut-derived LPS and Short-chain Fatty Acids" immunometabolic regulation of Lung IL-1beta, FFAR2 and FFAR3 Expression. Fatty Acids, Volatile 56-79 interleukin 1 alpha Homo sapiens 116-124 33546705-10 2021 Furthermore, E. coli KUB-36 metabolites and individual SCFA could affect inflammatory responses in lipopolysaccharide-induced THP-1 macrophage cells since they suppressed inflammatory cytokines IL-1beta, IL-6, IL-8 and TNF-alpha well as compared to the control, whilst inducing anti-inflammatory cytokine IL-10 expression. Fatty Acids, Volatile 55-59 interleukin 1 alpha Homo sapiens 194-202 32867889-9 2020 Gender-differentiated correlations of VFA with clinical and inflammatory variables were observed in age, FeNO, immunoglobulin E, blood total white cells and neutrophils, and sputum IL-1beta and IL-8. Fatty Acids, Volatile 38-41 interleukin 1 alpha Homo sapiens 181-189 32333962-7 2020 The SCFA mixture, as well as several individual SCFAs at the highest concentrations used in the mixture (15-236 muM), decreased the secretion of interleukin (IL)-1beta, monocyte chemoattractant protein (MCP)-1, tumor necrosis factor (TNF)-alpha, and cytotoxins by immune-stimulated THP-1 cells. Fatty Acids, Volatile 4-8 interleukin 1 alpha Homo sapiens 145-167 32333962-7 2020 The SCFA mixture, as well as several individual SCFAs at the highest concentrations used in the mixture (15-236 muM), decreased the secretion of interleukin (IL)-1beta, monocyte chemoattractant protein (MCP)-1, tumor necrosis factor (TNF)-alpha, and cytotoxins by immune-stimulated THP-1 cells. Fatty Acids, Volatile 48-53 interleukin 1 alpha Homo sapiens 145-167