PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34208638-5	2021	SCFA down-attenuated host pro-inflammatory IL-1beta, IL-6, and TNFalpha response predominantly through the TLR4 pathway, whereas MCFA augmented inflammation through TLR2.	Fatty Acids, Volatile	0-4	interleukin 1 alpha	Homo sapiens	43-51	
33851870-0	2021	Lung Immune Tone via Gut-Lung Axis: Gut-derived LPS and Short-chain Fatty Acids" immunometabolic regulation of Lung IL-1beta, FFAR2 and FFAR3 Expression.	Fatty Acids, Volatile	56-79	interleukin 1 alpha	Homo sapiens	116-124	
33546705-10	2021	Furthermore, E. coli KUB-36 metabolites and individual SCFA could affect inflammatory responses in lipopolysaccharide-induced THP-1 macrophage cells since they suppressed inflammatory cytokines IL-1beta, IL-6, IL-8 and TNF-alpha well as compared to the control, whilst inducing anti-inflammatory cytokine IL-10 expression.	Fatty Acids, Volatile	55-59	interleukin 1 alpha	Homo sapiens	194-202	
32333962-7	2020	The SCFA mixture, as well as several individual SCFAs at the highest concentrations used in the mixture (15-236 muM), decreased the secretion of interleukin (IL)-1beta, monocyte chemoattractant protein (MCP)-1, tumor necrosis factor (TNF)-alpha, and cytotoxins by immune-stimulated THP-1 cells.	Fatty Acids, Volatile	4-8	interleukin 1 alpha	Homo sapiens	145-167	
32333962-7	2020	The SCFA mixture, as well as several individual SCFAs at the highest concentrations used in the mixture (15-236 muM), decreased the secretion of interleukin (IL)-1beta, monocyte chemoattractant protein (MCP)-1, tumor necrosis factor (TNF)-alpha, and cytotoxins by immune-stimulated THP-1 cells.	Fatty Acids, Volatile	48-53	interleukin 1 alpha	Homo sapiens	145-167	
33085904-8	2021	SCFAs, products of microbial metabolism of complex carbohydrates of breastmilk oligosaccharides, have been found with this study to induce an anti-IL-1beta response that is associated with an upregulation of tight junctions and mucus genes in epithelial cells (H4 cells).	Fatty Acids, Volatile	0-5	interleukin 1 alpha	Homo sapiens	147-155	
32867889-9	2020	Gender-differentiated correlations of VFA with clinical and inflammatory variables were observed in age, FeNO, immunoglobulin E, blood total white cells and neutrophils, and sputum IL-1beta and IL-8.	Fatty Acids, Volatile	38-41	interleukin 1 alpha	Homo sapiens	181-189