PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34208638-5	2021	SCFA down-attenuated host pro-inflammatory IL-1beta, IL-6, and TNFalpha response predominantly through the TLR4 pathway, whereas MCFA augmented inflammation through TLR2.	Fatty Acids, Volatile	0-4	interleukin 6	Homo sapiens	53-57	
33546705-10	2021	Furthermore, E. coli KUB-36 metabolites and individual SCFA could affect inflammatory responses in lipopolysaccharide-induced THP-1 macrophage cells since they suppressed inflammatory cytokines IL-1beta, IL-6, IL-8 and TNF-alpha well as compared to the control, whilst inducing anti-inflammatory cytokine IL-10 expression.	Fatty Acids, Volatile	55-59	interleukin 6	Homo sapiens	204-208	
32383705-15	2020	As it was established the amount of bacteria producing short-chain fatty acids (SCFA) markedly decrease in T2-D, and treatment with SCFA reduced induction of TFN-alpha, IL-10 and IL-17 cytokines in contrast to IL-6, IFN-y and IL-22, without modification of their induction after using of SCFA.	Fatty Acids, Volatile	132-136	interleukin 6	Homo sapiens	210-214	
32383705-15	2020	As it was established the amount of bacteria producing short-chain fatty acids (SCFA) markedly decrease in T2-D, and treatment with SCFA reduced induction of TFN-alpha, IL-10 and IL-17 cytokines in contrast to IL-6, IFN-y and IL-22, without modification of their induction after using of SCFA.	Fatty Acids, Volatile	132-136	interleukin 6	Homo sapiens	210-214	
22059850-6	2012	RESULTS: Short-chain fatty acids, at 20 mM, induced interleukin (IL)-8, IL-6, and IL-1beta release, while lower levels (0.02-2 mM) did not induce cytokine secretion.	Fatty Acids, Volatile	9-32	interleukin 6	Homo sapiens	72-76	
34733901-8	2021	SCFAs can enhance the immune response by stimulating cytokine production (e.g. TNF-alpha, IL-2, IL-6, and IL-10) in the immune cells of the host.	Fatty Acids, Volatile	0-5	interleukin 6	Homo sapiens	96-100	
12353854-8	2002	These results indicate short-chain fatty acids beneficially increase small intestinal abundance of IL-1beta and IL-6 during total parenteral nutrition administration, while not affecting systemic production of these cytokines or intestinal inflammation.	Fatty Acids, Volatile	23-46	interleukin 6	Homo sapiens	112-116