PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8962566-1 1996 OBJECTIVES: To examine the feasibility of using milrinone to test pulmonary vascular reactivity in patients before heart transplantation, we tested the hypothesis that milrinone would lower pulmonary vascular resistance (PVR) in patients with severe heart failure. Milrinone 168-177 PVR cell adhesion molecule Homo sapiens 221-224 11726420-8 2001 Inhaled milrinone reduced PVR with a maximal effect (-20%, P < 0.001) at the largest concentration. Milrinone 8-17 PVR cell adhesion molecule Homo sapiens 26-29 11726420-9 2001 As compared with iPGI(2) alone, iPGI(2) + inhaled milrinone caused a further and prolonged reduction of PVR (-8%, P < 0.05) and increased stroke volume (+5%, P < 0.05). Milrinone 50-59 PVR cell adhesion molecule Homo sapiens 104-107 8962566-5 1996 The ability of milrinone to lower PVR in patients with heart failure has not been tested. Milrinone 15-24 PVR cell adhesion molecule Homo sapiens 34-37 8962566-7 1996 RESULTS: Milrinone decreased PVR in all patients. Milrinone 9-18 PVR cell adhesion molecule Homo sapiens 29-32 8962566-11 1996 The magnitude of the decrease in PVR correlated inversely with the milrinone-induced increase in cardiac output. Milrinone 67-76 PVR cell adhesion molecule Homo sapiens 33-36 8962566-12 1996 CONCLUSIONS: Bolus milrinone consistently decreases PVR in patients with pulmonary hypertension secondary to severe heart failure. Milrinone 19-28 PVR cell adhesion molecule Homo sapiens 52-55 19381522-10 2009 RESULTS: With milrinone administration, mean pulmonary artery pressure (MPAP) and PVR showed a comparable decrease in both groups. Milrinone 14-23 PVR cell adhesion molecule Homo sapiens 82-85 28717881-7 2017 Both inhaled milrinone and inhaled iloprost induced significant reductions in mean pulmonary artery pressure and PVR and significant increases in cardiac index in patients with post-CPB pulmonary hypertension. Milrinone 13-22 PVR cell adhesion molecule Homo sapiens 113-116 19381522-12 2009 MPAP and PVR returned to baseline values 60 minutes after termination of milrinone inhalation. Milrinone 73-82 PVR cell adhesion molecule Homo sapiens 9-12