PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3929434-5 1985 In contrast, exposure to 1.2 and 4 ppm NO2 decreased cytochrome P-450 on the 7th day. Nitrogen Dioxide 39-42 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 53-69 2495581-2 1989 The lung cytochrome P-450 decreased significantly after 1-week exposures to 10 and 15 ppm NO2 and showed a decreasing tendency after 2-week exposures to 6-10 ppm NO2. Nitrogen Dioxide 90-93 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 9-25 2495581-2 1989 The lung cytochrome P-450 decreased significantly after 1-week exposures to 10 and 15 ppm NO2 and showed a decreasing tendency after 2-week exposures to 6-10 ppm NO2. Nitrogen Dioxide 162-165 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 9-25 2495581-4 1989 These results show that the lung cytochrome P-450 decreases preferentially upon exposure to NO2 at higher concentrations. Nitrogen Dioxide 92-95 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 33-49 3019657-2 1986 In the lung, cytochrome P-450 decreased to 59% (P less than 0.01) and 57% (P less than 0.01) of the control values after 1 and 10 weeks of exposure to 4.0 ppm NO2, respectively, and remained at control levels at other exposure periods. Nitrogen Dioxide 159-162 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 13-29 3019657-5 1986 In the liver, cytochrome P-450 decreased to 72% (P less than 0.01), 70% (P less than 0.05), and 73% (P less than 0.05) of the control values after 1, 5, and 8 weeks of exposure to 4.0 ppm NO2, respectively, and remained at control levels at other exposure periods. Nitrogen Dioxide 188-191 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 14-30 3019657-10 1986 These results show that subacute exposures to 0.4-4.0 ppm NO2 caused a periodic reduction in microsomal cytochrome P-450 and mitochondrial succinate-cytochrome c reductase in the lung and in components of the microsomal electron-transport systems in the liver, whereas exposures to 1.2 and 4.0 ppm NO2 resulted in induction of the microsomal electron-transport systems in the kidney. Nitrogen Dioxide 58-61 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 104-171 3019657-10 1986 These results show that subacute exposures to 0.4-4.0 ppm NO2 caused a periodic reduction in microsomal cytochrome P-450 and mitochondrial succinate-cytochrome c reductase in the lung and in components of the microsomal electron-transport systems in the liver, whereas exposures to 1.2 and 4.0 ppm NO2 resulted in induction of the microsomal electron-transport systems in the kidney. Nitrogen Dioxide 298-301 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 104-171 6319120-5 1984 The NADPH-cytochrome c reductase activity and the cytochrome P-450 content were decreased to 82% (P less than 0.05) and 76% (P less than 0.05), respectively, at the fifth day of exposure to 10 ppm NO2. Nitrogen Dioxide 197-200 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 50-66 4057678-0 1985 [Changes in the content and activity of hepatic cytochrome P-450 in rats exposed to nitrogen dioxide for 30 days]. Nitrogen Dioxide 84-100 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 48-64 6515658-0 1984 Combined effect of nitrogen dioxide and cold stress on the activity of the hepatic cytochrome P-450 system in rats. Nitrogen Dioxide 19-35 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 83-99 6515658-1 1984 The combined effects of nitrogen dioxide (NO2) and cold stress were assessed on the cytochrome P-450 system by measuring microsomal protein content, cytochrome P-450 content, aminopyrine N-demethylase activity, and aniline hydroxylase activity in the liver of male Wistar rats exposed to 4 ppm NO2 and/or cold environment (4 degrees C) for 24 h, 14 days, and 30 days. Nitrogen Dioxide 24-40 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 84-100 6515658-1 1984 The combined effects of nitrogen dioxide (NO2) and cold stress were assessed on the cytochrome P-450 system by measuring microsomal protein content, cytochrome P-450 content, aminopyrine N-demethylase activity, and aniline hydroxylase activity in the liver of male Wistar rats exposed to 4 ppm NO2 and/or cold environment (4 degrees C) for 24 h, 14 days, and 30 days. Nitrogen Dioxide 42-45 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 84-100 6515658-3 1984 Interactions were observed in the effect on the cytochrome P-450 system when rats were exposed to NO2 and cold simultaneously. Nitrogen Dioxide 98-101 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 48-64 6515658-4 1984 There was a tendency that NO2 suppressed the increases in activities of the cytochrome P-450 system caused by cold of 24-h and 30-day exposure. Nitrogen Dioxide 26-29 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 76-92 6319120-6 1984 Exposure to 4 ppm NO2 also caused a significant decrease in the NADPH-cytochrome c reductase and the cytochrome P-450 content, which were lowered to 84% (P less than 0.05) of the control level at the fourth and seventh days, respectively. Nitrogen Dioxide 18-21 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus 101-117