PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
4057678-0	1985	[Changes in the content and activity of hepatic cytochrome P-450 in rats exposed to nitrogen dioxide for 30 days].	Nitrogen Dioxide	84-100	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	48-64	
3929434-5	1985	In contrast, exposure to 1.2 and 4 ppm NO2 decreased cytochrome P-450 on the 7th day.	Nitrogen Dioxide	39-42	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	53-69	
2495581-2	1989	The lung cytochrome P-450 decreased significantly after 1-week exposures to 10 and 15 ppm NO2 and showed a decreasing tendency after 2-week exposures to 6-10 ppm NO2.	Nitrogen Dioxide	90-93	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	9-25	
2495581-2	1989	The lung cytochrome P-450 decreased significantly after 1-week exposures to 10 and 15 ppm NO2 and showed a decreasing tendency after 2-week exposures to 6-10 ppm NO2.	Nitrogen Dioxide	162-165	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	9-25	
2495581-4	1989	These results show that the lung cytochrome P-450 decreases preferentially upon exposure to NO2 at higher concentrations.	Nitrogen Dioxide	92-95	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	33-49	
3019657-2	1986	In the lung, cytochrome P-450 decreased to 59% (P less than 0.01) and 57% (P less than 0.01) of the control values after 1 and 10 weeks of exposure to 4.0 ppm NO2, respectively, and remained at control levels at other exposure periods.	Nitrogen Dioxide	159-162	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	13-29	
3019657-5	1986	In the liver, cytochrome P-450 decreased to 72% (P less than 0.01), 70% (P less than 0.05), and 73% (P less than 0.05) of the control values after 1, 5, and 8 weeks of exposure to 4.0 ppm NO2, respectively, and remained at control levels at other exposure periods.	Nitrogen Dioxide	188-191	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	14-30	
3019657-10	1986	These results show that subacute exposures to 0.4-4.0 ppm NO2 caused a periodic reduction in microsomal cytochrome P-450 and mitochondrial succinate-cytochrome c reductase in the lung and in components of the microsomal electron-transport systems in the liver, whereas exposures to 1.2 and 4.0 ppm NO2 resulted in induction of the microsomal electron-transport systems in the kidney.	Nitrogen Dioxide	58-61	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	104-171	
3019657-10	1986	These results show that subacute exposures to 0.4-4.0 ppm NO2 caused a periodic reduction in microsomal cytochrome P-450 and mitochondrial succinate-cytochrome c reductase in the lung and in components of the microsomal electron-transport systems in the liver, whereas exposures to 1.2 and 4.0 ppm NO2 resulted in induction of the microsomal electron-transport systems in the kidney.	Nitrogen Dioxide	298-301	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	104-171	
6515658-0	1984	Combined effect of nitrogen dioxide and cold stress on the activity of the hepatic cytochrome P-450 system in rats.	Nitrogen Dioxide	19-35	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	83-99	
6515658-1	1984	The combined effects of nitrogen dioxide (NO2) and cold stress were assessed on the cytochrome P-450 system by measuring microsomal protein content, cytochrome P-450 content, aminopyrine N-demethylase activity, and aniline hydroxylase activity in the liver of male Wistar rats exposed to 4 ppm NO2 and/or cold environment (4 degrees C) for 24 h, 14 days, and 30 days.	Nitrogen Dioxide	24-40	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	84-100	
6515658-1	1984	The combined effects of nitrogen dioxide (NO2) and cold stress were assessed on the cytochrome P-450 system by measuring microsomal protein content, cytochrome P-450 content, aminopyrine N-demethylase activity, and aniline hydroxylase activity in the liver of male Wistar rats exposed to 4 ppm NO2 and/or cold environment (4 degrees C) for 24 h, 14 days, and 30 days.	Nitrogen Dioxide	42-45	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	84-100	
6515658-3	1984	Interactions were observed in the effect on the cytochrome P-450 system when rats were exposed to NO2 and cold simultaneously.	Nitrogen Dioxide	98-101	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	48-64	
6515658-4	1984	There was a tendency that NO2 suppressed the increases in activities of the cytochrome P-450 system caused by cold of 24-h and 30-day exposure.	Nitrogen Dioxide	26-29	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	76-92	
6319120-5	1984	The NADPH-cytochrome c reductase activity and the cytochrome P-450 content were decreased to 82% (P less than 0.05) and 76% (P less than 0.05), respectively, at the fifth day of exposure to 10 ppm NO2.	Nitrogen Dioxide	197-200	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	50-66	
6319120-6	1984	Exposure to 4 ppm NO2 also caused a significant decrease in the NADPH-cytochrome c reductase and the cytochrome P-450 content, which were lowered to 84% (P less than 0.05) of the control level at the fourth and seventh days, respectively.	Nitrogen Dioxide	18-21	cytochrome P450, family 2, subfamily g, polypeptide 1	Rattus norvegicus	101-117