PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10380161-7 1999 In the BL, NO2 exposure caused increases in polymorphonuclear neutrophils (PMNs), interleukin 6 (IL-6), IL-8, alpha1-antitrypsin, and tissue plasminogen activator, and decreases in epithelial cells. Nitrogen Dioxide 11-14 serpin family A member 1 Homo sapiens 110-128 2055821-5 1991 NO2 exposure in the absence of vitamin supplementation caused a significant decrease in the elastase inhibitory capacity (EIC) of the alveolar lining fluid in the control group but not in the vitamin-supplemented group [control 3.67 +/- 0.32 micrograms alpha 1-PI/micrograms porcine pancreatic elastase (PPE) vs. vitamin-supplemented 2.75 +/- 0.17, P less than 0.03]. Nitrogen Dioxide 0-3 serpin family A member 1 Homo sapiens 253-263 2787317-1 1989 Previously we demonstrated that in vivo exposure of humans to NO2 resulted in significant inactivation of alpha 1-protease inhibitor (alpha 1-PI) in the bronchoalveolar lavage fluid. Nitrogen Dioxide 62-65 serpin family A member 1 Homo sapiens 106-132 2787317-1 1989 Previously we demonstrated that in vivo exposure of humans to NO2 resulted in significant inactivation of alpha 1-protease inhibitor (alpha 1-PI) in the bronchoalveolar lavage fluid. Nitrogen Dioxide 62-65 serpin family A member 1 Homo sapiens 134-144 2787317-2 1989 However, alpha 1-PI retains its elastase inhibitory activity in vitro when exposed to 10 times the concentration of NO2 used in vivo. Nitrogen Dioxide 116-119 serpin family A member 1 Homo sapiens 9-19 2787317-5 1989 alpha 1-PI in solutions containing phosphate buffer (control), 0.1 mM stearic acid (saturated fatty acid, 18:0), or 0.1 mM linoleic acid (polyunsaturated fatty acid, 18:2) was exposed to either N2 or NO2 (50 ppm for 4 h). Nitrogen Dioxide 200-203 serpin family A member 1 Homo sapiens 0-10 2787317-6 1989 Elastase inhibitory capacity of alpha 1-PI was significantly diminished in the presence of 0.1 mM linoleic acid and under NO2 atmosphere (75 +/- 8% of control, P less than 0.01), whereas there was no change in elastase inhibitory capacity of alpha 1-PI in the presence or absence (buffer only) of 0.1 mM stearic acid under a similar condition (109 +/- 11 and 94 +/- 6%, respectively). Nitrogen Dioxide 122-125 serpin family A member 1 Homo sapiens 32-42 3498415-0 1987 Acute effect of nitrogen dioxide exposure on the functional activity of alpha-1-protease inhibitor in bronchoalveolar lavage fluid of normal subjects. Nitrogen Dioxide 16-32 serpin family A member 1 Homo sapiens 72-98 3498415-2 1987 We examined the effect of NO2 exposure on the functional activity against pancreatic elastase of alpha-1-protease inhibitor (alpha 1PI) in bronchoalveolar lavage (BAL) fluid of nonsmoking subjects. Nitrogen Dioxide 26-29 serpin family A member 1 Homo sapiens 97-123 3498415-2 1987 We examined the effect of NO2 exposure on the functional activity against pancreatic elastase of alpha-1-protease inhibitor (alpha 1PI) in bronchoalveolar lavage (BAL) fluid of nonsmoking subjects. Nitrogen Dioxide 26-29 serpin family A member 1 Homo sapiens 125-134 3498415-6 1987 Exposure to NO2 caused a 45% decrease in functional activity of alpha 1PI in BAL. Nitrogen Dioxide 12-15 serpin family A member 1 Homo sapiens 64-73 3498415-11 1987 These results showed that nonsmoking subjects exposed to relatively low concentrations of NO2 for a short time have a significant inactivation of alpha 1PI in the lower respiratory tract fluid than did nonsmoking control subjects. Nitrogen Dioxide 90-93 serpin family A member 1 Homo sapiens 146-155 2444033-0 1987 [Serum alpha 1-antitrypsin and alpha 2-macroglobulin levels in persons exposed to benzene, hydrogen cyanide, sulfur dioxide and nitrogen dioxide]. Nitrogen Dioxide 128-144 serpin family A member 1 Homo sapiens 7-26 23033993-8 2012 Exposure to both NO2 and PM(2.5)CAPs increased BAL alpha1-antitrypsin, mean t wave amplitude, the low frequency components of HRV and the LF/HF ratio. Nitrogen Dioxide 17-20 serpin family A member 1 Homo sapiens 51-69