PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10380161-7	1999	In the BL, NO2 exposure caused increases in polymorphonuclear neutrophils (PMNs), interleukin 6 (IL-6), IL-8, alpha1-antitrypsin, and tissue plasminogen activator, and decreases in epithelial cells.	Nitrogen Dioxide	11-14	serpin family A member 1	Homo sapiens	110-128	
2055821-5	1991	NO2 exposure in the absence of vitamin supplementation caused a significant decrease in the elastase inhibitory capacity (EIC) of the alveolar lining fluid in the control group but not in the vitamin-supplemented group [control 3.67 +/- 0.32 micrograms alpha 1-PI/micrograms porcine pancreatic elastase (PPE) vs. vitamin-supplemented 2.75 +/- 0.17, P less than 0.03].	Nitrogen Dioxide	0-3	serpin family A member 1	Homo sapiens	253-263	
2787317-1	1989	Previously we demonstrated that in vivo exposure of humans to NO2 resulted in significant inactivation of alpha 1-protease inhibitor (alpha 1-PI) in the bronchoalveolar lavage fluid.	Nitrogen Dioxide	62-65	serpin family A member 1	Homo sapiens	106-132	
2787317-1	1989	Previously we demonstrated that in vivo exposure of humans to NO2 resulted in significant inactivation of alpha 1-protease inhibitor (alpha 1-PI) in the bronchoalveolar lavage fluid.	Nitrogen Dioxide	62-65	serpin family A member 1	Homo sapiens	134-144	
2787317-2	1989	However, alpha 1-PI retains its elastase inhibitory activity in vitro when exposed to 10 times the concentration of NO2 used in vivo.	Nitrogen Dioxide	116-119	serpin family A member 1	Homo sapiens	9-19	
2787317-5	1989	alpha 1-PI in solutions containing phosphate buffer (control), 0.1 mM stearic acid (saturated fatty acid, 18:0), or 0.1 mM linoleic acid (polyunsaturated fatty acid, 18:2) was exposed to either N2 or NO2 (50 ppm for 4 h).	Nitrogen Dioxide	200-203	serpin family A member 1	Homo sapiens	0-10	
2787317-6	1989	Elastase inhibitory capacity of alpha 1-PI was significantly diminished in the presence of 0.1 mM linoleic acid and under NO2 atmosphere (75 +/- 8% of control, P less than 0.01), whereas there was no change in elastase inhibitory capacity of alpha 1-PI in the presence or absence (buffer only) of 0.1 mM stearic acid under a similar condition (109 +/- 11 and 94 +/- 6%, respectively).	Nitrogen Dioxide	122-125	serpin family A member 1	Homo sapiens	32-42	
2444033-0	1987	[Serum alpha 1-antitrypsin and alpha 2-macroglobulin levels in persons exposed to benzene, hydrogen cyanide, sulfur dioxide and nitrogen dioxide].	Nitrogen Dioxide	128-144	serpin family A member 1	Homo sapiens	7-26	
23033993-8	2012	Exposure to both NO2 and PM(2.5)CAPs increased BAL alpha1-antitrypsin, mean t wave amplitude, the low frequency components of HRV and the LF/HF ratio.	Nitrogen Dioxide	17-20	serpin family A member 1	Homo sapiens	51-69	
3498415-0	1987	Acute effect of nitrogen dioxide exposure on the functional activity of alpha-1-protease inhibitor in bronchoalveolar lavage fluid of normal subjects.	Nitrogen Dioxide	16-32	serpin family A member 1	Homo sapiens	72-98	
3498415-2	1987	We examined the effect of NO2 exposure on the functional activity against pancreatic elastase of alpha-1-protease inhibitor (alpha 1PI) in bronchoalveolar lavage (BAL) fluid of nonsmoking subjects.	Nitrogen Dioxide	26-29	serpin family A member 1	Homo sapiens	97-123	
3498415-2	1987	We examined the effect of NO2 exposure on the functional activity against pancreatic elastase of alpha-1-protease inhibitor (alpha 1PI) in bronchoalveolar lavage (BAL) fluid of nonsmoking subjects.	Nitrogen Dioxide	26-29	serpin family A member 1	Homo sapiens	125-134	
3498415-6	1987	Exposure to NO2 caused a 45% decrease in functional activity of alpha 1PI in BAL.	Nitrogen Dioxide	12-15	serpin family A member 1	Homo sapiens	64-73	
3498415-11	1987	These results showed that nonsmoking subjects exposed to relatively low concentrations of NO2 for a short time have a significant inactivation of alpha 1PI in the lower respiratory tract fluid than did nonsmoking control subjects.	Nitrogen Dioxide	90-93	serpin family A member 1	Homo sapiens	146-155