PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10066641-8	1999	We observed an increased IL-1beta-, IL-6-, IL-8- and TNF-alpha-specific mRNA expression of particle or fibre exposed AM, which was decreased after an additional NO2 exposure.	Nitrogen Dioxide	161-164	interleukin 6	Homo sapiens	36-47	
10380161-7	1999	In the BL, NO2 exposure caused increases in polymorphonuclear neutrophils (PMNs), interleukin 6 (IL-6), IL-8, alpha1-antitrypsin, and tissue plasminogen activator, and decreases in epithelial cells.	Nitrogen Dioxide	11-14	interleukin 6	Homo sapiens	82-95	
10380161-7	1999	In the BL, NO2 exposure caused increases in polymorphonuclear neutrophils (PMNs), interleukin 6 (IL-6), IL-8, alpha1-antitrypsin, and tissue plasminogen activator, and decreases in epithelial cells.	Nitrogen Dioxide	11-14	interleukin 6	Homo sapiens	97-101	
28481326-0	2017	The Dose-Response Association between Nitrogen Dioxide Exposure and Serum Interleukin-6 Concentrations.	Nitrogen Dioxide	38-54	interleukin 6	Homo sapiens	74-87	
8747002-7	1996	Exposure for 30 min to NO2 induced a significant decrease of LPS-stimulated IL-1 Beta, IL-6, IL-8, and TNF-alpha (p < .05).	Nitrogen Dioxide	23-26	interleukin 6	Homo sapiens	87-91	
8747002-10	1996	NO2 exposure of LPS-stimulated AM resulted in a functional impairment of AM after NO2 exposure regarding IL-1 beta, IL-6, IL-8, and TNF-alpha.	Nitrogen Dioxide	0-3	interleukin 6	Homo sapiens	116-120	
8584542-5	1995	When compared to air-exposed cells, NO2 induced increases in IL-6 (23.4-fold) and IL-8 (30.9-fold) mRNA abundance.	Nitrogen Dioxide	36-39	interleukin 6	Homo sapiens	61-65	
8584542-6	1995	The NO2-dependent increases in mRNA expression reached a maximum between 0 and 1 h post exposure and returned to baseline levels within 24 h. IL-6 and IL-8 proteins as measured by enzyme-linked immunosorbent assays (ELISA) were also elevated in supernatants recovered from NO2-exposed BEAS-2B cells.	Nitrogen Dioxide	4-7	interleukin 6	Homo sapiens	142-146	
34879788-4	2021	Generalized estimating equation was used to evaluate the association between exposure to PM2.5 and NO2 and the following serum cytokine levels on the 7 days preceding clinical assessment and serum collection: MCP1, IL-6, IL-8, IL-10, IL-17, IFN-alpha, and TNF-alpha.	Nitrogen Dioxide	99-102	interleukin 6	Homo sapiens	215-219	
28669936-7	2017	RESULTS: A 10 mug/m3 increase of NO2 exposure during infancy was associated with a 13.6% (95% confidence interval (CI): 0.8; 28.1%) increase in interleukin-6 (IL-6) levels, as well as with a 27.8% (95% CI: 4.6, 56.2%) increase in IL-10 levels, the latter limited to children with asthma.	Nitrogen Dioxide	33-36	interleukin 6	Homo sapiens	144-157	
28669936-7	2017	RESULTS: A 10 mug/m3 increase of NO2 exposure during infancy was associated with a 13.6% (95% confidence interval (CI): 0.8; 28.1%) increase in interleukin-6 (IL-6) levels, as well as with a 27.8% (95% CI: 4.6, 56.2%) increase in IL-10 levels, the latter limited to children with asthma.	Nitrogen Dioxide	33-36	interleukin 6	Homo sapiens	159-163	
28481326-6	2017	We found a positive association with increasing serum IL-6 concentration (geometric mean 1.20 (95% CI: 1.1 to 1.3, p = 0.001) per quartile increase in NO2).	Nitrogen Dioxide	151-154	interleukin 6	Homo sapiens	54-58	
28481326-8	2017	However, there was some evidence consistent with serum IL-6 being on the causal pathway between NO2 and cardiovascular risk.	Nitrogen Dioxide	96-99	interleukin 6	Homo sapiens	55-59	
25763062-2	2014	A strong over expression of IL-6, IL-8, IFNalpha and IFNgamma was observed in bursa at 3 days post inoculation together with an increase in splenic NO2 release.	Nitrogen Dioxide	148-151	interleukin 6	Homo sapiens	28-32	
27820923-5	2016	NO2 exposure resulted in a concentration-dependent release of IL-6, but not IL-8 release.	Nitrogen Dioxide	0-3	interleukin 6	Homo sapiens	62-66	
27820923-6	2016	The coexposure of 0.1 ppm NO2 and Der p 1, or 1 ppm NO2 and Der p 1 significantly increased both IL-6 and IL-8 release.	Nitrogen Dioxide	26-29	interleukin 6	Homo sapiens	97-101	
27820923-6	2016	The coexposure of 0.1 ppm NO2 and Der p 1, or 1 ppm NO2 and Der p 1 significantly increased both IL-6 and IL-8 release.	Nitrogen Dioxide	52-55	interleukin 6	Homo sapiens	97-101	
27820923-4	2016	Exposure to 0.1, 1 and 10 ppm NO2 or synthetic air as a control was performed for 1 h. Subsequently, the cells were exposed to Der p 1 for 24 h. The release of interleukin (IL)-6 and IL-8 was measured by ELISA, and the production of IL-6 mRNA and IL-8 mRNA was measured by RT-PCR.	Nitrogen Dioxide	30-33	interleukin 6	Homo sapiens	160-178	
24056475-12	2013	One-year traffic-NO2 exposure was associated with higher IL-6 levels with each additional IL6-174C allele, and 1-year heating-SO2 exposure with higher levels of TNF-alpha in TNF-308AA homozygotes versus -308G carriers.	Nitrogen Dioxide	17-20	interleukin 6	Homo sapiens	57-61	
24056475-12	2013	One-year traffic-NO2 exposure was associated with higher IL-6 levels with each additional IL6-174C allele, and 1-year heating-SO2 exposure with higher levels of TNF-alpha in TNF-308AA homozygotes versus -308G carriers.	Nitrogen Dioxide	17-20	interleukin 6	Homo sapiens	90-93