PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25319474-3 2015 In this study, we evaluate the effect of two fertilizing drugs, clomiphene citrate and estradiol, on the activation of Erk1/2 and the viability of two breast cancer cell lines, MCF-7 (hormone dependent) and BT20 (hormone independent).We show that both drugs induce Erk1/2 phosphorylation in MCF-7 and BT20 cells despite their opposite effect on cell viability. Clomiphene 64-82 mitogen-activated protein kinase 3 Homo sapiens 119-125 25319474-3 2015 In this study, we evaluate the effect of two fertilizing drugs, clomiphene citrate and estradiol, on the activation of Erk1/2 and the viability of two breast cancer cell lines, MCF-7 (hormone dependent) and BT20 (hormone independent).We show that both drugs induce Erk1/2 phosphorylation in MCF-7 and BT20 cells despite their opposite effect on cell viability. Clomiphene 64-82 mitogen-activated protein kinase 3 Homo sapiens 265-271