PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10332029-1 1999 A novel gene, designated PQBP-1, which encodes a 265 residue protein that binds to the polyglutamine tract of the brain-specific transcription factor Brn-2, was identified. polyglutamine 87-100 polyglutamine binding protein 1 Rattus norvegicus 25-31 10332029-2 1999 PQBP-1, which also interacts with the polyglutamine tract of triplet repeat disease gene products, binds with a higher affinity to an expanded polyglutamine tract. polyglutamine 38-51 polyglutamine binding protein 1 Rattus norvegicus 0-6 10332029-2 1999 PQBP-1, which also interacts with the polyglutamine tract of triplet repeat disease gene products, binds with a higher affinity to an expanded polyglutamine tract. polyglutamine 143-156 polyglutamine binding protein 1 Rattus norvegicus 0-6 10332029-3 1999 PQBP-1 has several functional domains, including hepta- and di-amino acid repeat sequences rich in polar residues essential for its interaction with the polyglutamine tract, a WWP/WW domain which binds to proline-rich motifs in other proteins, a putative nuclear localization signal sequence and a C2domain implicated in Ca2+-dependent phospholipid signaling. polyglutamine 153-166 polyglutamine binding protein 1 Rattus norvegicus 0-6 10332029-7 1999 These results suggest that PQBP-1 mediates important cellular functions under physiological and pathological conditions via its interaction with polyglutamine tracts. polyglutamine 145-158 polyglutamine binding protein 1 Rattus norvegicus 27-33