PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30038412-5	2018	Conversely, loss of UBR5 increases HTT levels and triggers polyQ-expanded aggregation in HD-iPSCs.	polyglutamine	59-64	ubiquitin protein ligase E3 component n-recognin 5	Homo sapiens	20-24	
30038412-6	2018	Moreover, UBR5 knockdown hastens polyQ-expanded aggregation and neurotoxicity in invertebrate models.	polyglutamine	33-38	ubiquitin protein ligase E3 component n-recognin 5	Homo sapiens	10-14	
30038412-7	2018	Notably, UBR5 overexpression induces polyubiquitination and degradation of mutant HTT, reducing polyQ-expanded aggregates in HD-cell models.	polyglutamine	96-101	ubiquitin protein ligase E3 component n-recognin 5	Homo sapiens	9-13