PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12393801-7 2002 Through the over-expression of a mutant of the SUMO-1 activating enzyme Uba2, we further show that poly(Q)-induced degeneration is intensified when the cellular SUMO-1 protein conjugation pathway is altered. polyglutamine 99-106 Ubiquitin-like activating enzyme 2 Drosophila melanogaster 72-76