PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12598532-8 2003 We suggest that reduction of HSP70 by expanded polyglutamine is implicated in aggregation and inhibition of M3/6 and in activation of JNK and AP-1. polyglutamine 47-60 jun proto-oncogene Mus musculus 142-146 21832068-9 2011 Taken together, these results demonstrated that CRAG enhances the cell survival signal against the accumulation of unfolded proteins, including polyQ, through not only proteasome activation, but also the activation of c-Fos-dependent AP-1. polyglutamine 144-149 jun proto-oncogene Mus musculus 234-238 17189700-0 2007 Preventing polyglutamine-induced activation of c-Jun delays neuronal dysfunction in a mouse model of SCA7 retinopathy. polyglutamine 11-24 jun proto-oncogene Mus musculus 47-52 12598532-2 2003 Using cell and mouse models, we have shown that expanded polyglutamine led to activation of the stress kinase JNK and the transcription factor AP-1, which are implicated in neuronal death. polyglutamine 57-70 jun proto-oncogene Mus musculus 143-147