PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18782221-3 2008 Here we present direct evidence that CDC-48.1 and CDC-48.2 suppress the aggregation of a huntingtin (Htt) exon1 fragment containing an expanded polyQ repeat in vitro. polyglutamine 144-149 Transitional endoplasmic reticulum ATPase homolog 1 Caenorhabditis elegans 37-45 18782221-0 2008 p97 Homologs from Caenorhabditis elegans, CDC-48.1 and CDC-48.2, suppress the aggregate formation of huntingtin exon1 containing expanded polyQ repeat. polyglutamine 138-143 Transitional endoplasmic reticulum ATPase homolog 1 Caenorhabditis elegans 42-50 18782221-2 2008 We have reported that the aggregation of the polyQ-expanded protein is partially suppressed by co-expression of either of two homologs of an AAA chaperone p97, CDC-48.1 or CDC-48.2, in Caenorhabditis elegans, but how p97 regulates the aggregation of polyQ-expanded proteins remains unclear. polyglutamine 45-50 Transitional endoplasmic reticulum ATPase homolog 1 Caenorhabditis elegans 160-168 18782221-2 2008 We have reported that the aggregation of the polyQ-expanded protein is partially suppressed by co-expression of either of two homologs of an AAA chaperone p97, CDC-48.1 or CDC-48.2, in Caenorhabditis elegans, but how p97 regulates the aggregation of polyQ-expanded proteins remains unclear. polyglutamine 250-255 Transitional endoplasmic reticulum ATPase homolog 1 Caenorhabditis elegans 160-168