PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15590702-4 2005 Here, we report that polyglutamine-induced cell death was dramatically suppressed in flies lacking Dark, the fly homolog of human Apaf-1, a key regulator of apoptosis. polyglutamine 21-34 dk Drosophila melanogaster 99-103 15590702-5 2005 Dark appeared to play a role in the accumulation of polyglutamine-containing aggregates. polyglutamine 52-65 dk Drosophila melanogaster 0-4 15590702-7 2005 Expanded polyglutamine induced a marked increase in expression of Dark, and Dark was observed to colocalize with ubiquitinated protein aggregates. polyglutamine 9-22 dk Drosophila melanogaster 66-70 15590702-7 2005 Expanded polyglutamine induced a marked increase in expression of Dark, and Dark was observed to colocalize with ubiquitinated protein aggregates. polyglutamine 9-22 dk Drosophila melanogaster 76-80