PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28384474-4 2017 Huntingtin-linked polyglutamine initially accumulates in nuclei, leading to disruption of nuclear envelope architecture, partial sequestration of factors essential for nucleocytoplasmic transport (Gle1 and RanGAP1), and intranuclear accumulation of mRNA. polyglutamine 18-31 GLE1 RNA export mediator (yeast) Mus musculus 197-201