PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20065067-2 2010 RNAi-mediated downregulation of the large nuclear hsromega-n transcript, which organizes the nucleoplasmic omega speckles, suppressed the enhancement of poly(Q) toxicity brought about by reduced availability of the heterogeneous nuclear ribonucleoprotein (hnRNP) Hrb87F and of the transcriptional regulator, cAMP response element binding (CREB) binding protein (CBP). polyglutamine 153-160 sarcoplasmic calcium-binding protein Drosophila melanogaster 362-365