PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12524342-2	2002	The normal cellular function of ataxin-2 and the mechanism by which polyglutamine expansion of ataxin-2 causes neurodegeneration remain unknown.	polyglutamine	68-81	Ataxin-2	Drosophila melanogaster	95-103	
18166084-2	2007	SCA1 and SCA2 are two ataxias caused by expansion of polyglutamine tracts in Ataxin-1 (ATXN1) and Ataxin-2 (ATXN2), respectively, two proteins that are otherwise unrelated.	polyglutamine	53-66	Ataxin-2	Drosophila melanogaster	9-13	
18166084-2	2007	SCA1 and SCA2 are two ataxias caused by expansion of polyglutamine tracts in Ataxin-1 (ATXN1) and Ataxin-2 (ATXN2), respectively, two proteins that are otherwise unrelated.	polyglutamine	53-66	Ataxin-2	Drosophila melanogaster	98-106	
16835262-1	2006	Mutations resulting in the expansion of a polyglutamine tract in the protein ataxin-2 give rise to the neurodegenerative disorders spinocerebellar ataxia type 2 and Parkinson"s disease.	polyglutamine	42-55	Ataxin-2	Drosophila melanogaster	77-85	
16835262-2	2006	The normal cellular function of ataxin-2 and the mechanism by which polyglutamine expansion of ataxin-2 causes neurodegeneration are unknown.	polyglutamine	68-81	Ataxin-2	Drosophila melanogaster	95-103	
16835262-8	2006	Our results raise the possibility that polyglutamine expansions within ataxin-2 cause neurodegeneration by interfering with the translational regulation of particular mRNAs.	polyglutamine	39-52	Ataxin-2	Drosophila melanogaster	71-79	
34977501-2	2022	Atx2 undergoes polyglutamine expansion leading to amyotrophic lateral sclerosis (ALS) or spinocerebellar ataxia type 2 (SCA2).	polyglutamine	15-28	Ataxin-2	Drosophila melanogaster	0-4	
34077532-3	2021	The sequence encoding the polyQ repeat also varies with disease presentation: a pure CAG repeat is associated with SCA2, whereas the CAG repeat in ALS and parkinsonism is typically interrupted with the glutamine encoding CAA codon.	polyglutamine	26-31	Ataxin-2	Drosophila melanogaster	115-119	
34077532-8	2021	These data indicate that ataxin-2 encoded by a pure CAG vs interrupted CAA/G polyQ repeat domain is associated with differential toxicity, indicating that mechanisms associated with the purity of the sequence of the polyQ domain contribute to disease.	polyglutamine	77-82	Ataxin-2	Drosophila melanogaster	25-33	
34077532-8	2021	These data indicate that ataxin-2 encoded by a pure CAG vs interrupted CAA/G polyQ repeat domain is associated with differential toxicity, indicating that mechanisms associated with the purity of the sequence of the polyQ domain contribute to disease.	polyglutamine	216-221	Ataxin-2	Drosophila melanogaster	25-33