PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32453327-9 2020 The mechanism proposed is the activation of DAF-16, HSP-16.2 and SOD-3 in whole body tissues to increase the antioxidant capacity and regulation of proteostasis, decreasing PolyQ aggregation and toxicity and reducing ROS levels, leading to an increase in lifespan, and healthspan. polyglutamine 173-178 Heat shock protein hsp-16.2;SHSP domain-containing protein Caenorhabditis elegans 52-60