PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22426400-0 2012 Huntingtin with an expanded polyglutamine repeat affects the Jab1-p27(Kip1) pathway. polyglutamine 28-41 COP9 signalosome subunit 5 Homo sapiens 61-65 22426400-3 2012 In this study, we report on a novel target of expanded polyglutamine stretches, the transcriptional coactivator Jun activation domain-binding protein 1 (Jab1), which shares DNA-sequence-specific transcription factor targets with CBP. polyglutamine 55-68 COP9 signalosome subunit 5 Homo sapiens 112-151 22426400-3 2012 In this study, we report on a novel target of expanded polyglutamine stretches, the transcriptional coactivator Jun activation domain-binding protein 1 (Jab1), which shares DNA-sequence-specific transcription factor targets with CBP. polyglutamine 55-68 COP9 signalosome subunit 5 Homo sapiens 153-157 22426400-5 2012 We found that Jab1 accumulates in aggregates when co-expressed with either expanded polyglutamine stretches or N-terminal fragments of mutant htt. polyglutamine 84-97 COP9 signalosome subunit 5 Homo sapiens 14-18 22426400-6 2012 In addition, the coactivator function of Jab1 was suppressed both by aggregated expanded polyglutamine solely and by mutant htt. polyglutamine 89-102 COP9 signalosome subunit 5 Homo sapiens 41-45