PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23347954-4 2013 Rho-kinase (ROCK) inhibitor Y27632 reduced brain level of polyglutamine-expanded huntingtin in HD transgenic mouse. polyglutamine 58-71 Rho associated coiled-coil containing protein kinase 1 Homo sapiens 12-16 23347954-5 2013 Therefore, we tested the possibility that ROCK inhibitors, Y27632, H1152 and GSK429286, downregulate protein expression of polyglutamine-expanded ataxin-3-Q79. polyglutamine 123-136 Rho associated coiled-coil containing protein kinase 1 Homo sapiens 42-46 19278999-3 2009 Whereas many molecules able to reduce the polyQ accumulation and aggregation have been identified, including several Rho kinase (ROCK) inhibitors, it remains very important to determine the mechanism of action of the potential drugs. polyglutamine 42-47 Rho associated coiled-coil containing protein kinase 1 Homo sapiens 129-133