PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9337072-4 1997 Co-administration of bryostatin 1 with mezerein before ara-C prevented down-regulation of c-Myc and augmented cell death, whereas co-treatment with the calcium ionophore A23187 (250 nM) and bryostatin 1 reduced c-Myc levels by 80% and abrogated the increase in ara-C-induced apoptosis. mezerein 39-47 MYC proto-oncogene, bHLH transcription factor Homo sapiens 90-95 7566979-5 1995 Induction of both terminal differentiation and reversible differentiation (MEZ treatment) results in a temporal decrease in DNA synthesis and the percentage of cells in S phase and a decrease in the expression of cell cycle and growth regulated genes, including cdc2, cyclin A, cyclin B, histone H1, histone H4, nm23-H1, p53 and c-myc. mezerein 75-78 MYC proto-oncogene, bHLH transcription factor Homo sapiens 329-334