PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1429539-2 1992 The model is based on analogies to the known structures of the MgATP site on adenylate kinase and the guanine nucleotide sites on elongation factor Tu (Ef-Tu) and the ras p21 protein. Adenosine Triphosphate 63-68 H3 histone pseudogene 16 Homo sapiens 171-174 10918446-5 2000 This mitochondrial damage occurs before an estrangement of the procaspase 3/p21 complex, and we demonstrate that intracellular ATP-deprivation also initiates an estrangement of procaspase 3/p21 complex formation and accelerates Fas-mediated cell death. Adenosine Triphosphate 127-130 H3 histone pseudogene 16 Homo sapiens 76-79 10918446-5 2000 This mitochondrial damage occurs before an estrangement of the procaspase 3/p21 complex, and we demonstrate that intracellular ATP-deprivation also initiates an estrangement of procaspase 3/p21 complex formation and accelerates Fas-mediated cell death. Adenosine Triphosphate 127-130 H3 histone pseudogene 16 Homo sapiens 190-193 9476915-5 1998 Renaturation of apical membrane proteins within polyacrylamide gels showed that p19s and p21s autophosphorylated with either gamma[32P]GTP or gamma[32P]ATP as substrates, suggesting that the two proteins were kinases. Adenosine Triphosphate 152-155 H3 histone pseudogene 16 Homo sapiens 89-92 8076673-1 1994 In contrast to the previous topological model of the ATP binding domain of the F1-ATPase beta subunit based on analogies to those of ras p21 and adenylate kinase, a more consistent model can be constructed with the known structure of the recA protein as a reference. Adenosine Triphosphate 53-56 H3 histone pseudogene 16 Homo sapiens 137-140 20351180-6 2010 Our results thus suggest that p400 represses basal p21 gene expression through dual mechanisms that include the direct inhibition of TIP60 enzymatic activity described here and the previously described ATP-dependent positioning of H2A.Z at the promoter. Adenosine Triphosphate 202-205 H3 histone pseudogene 16 Homo sapiens 51-54 10918446-7 2000 Here, we report that the mitochondrial role, especially for ATP synthesis, and PKA are necessary for the procaspase 3/p21 complex formation to resist Fas-mediated cell death. Adenosine Triphosphate 60-63 H3 histone pseudogene 16 Homo sapiens 118-121 7881906-7 1994 The presence of sulphate ions in the crystals and comparisons with the related Ha-ras-p21 oncogene product are used to infer the ATP-binding site, corroborated by the difference electron density for the ATP analogue AMP-PNP. Adenosine Triphosphate 129-132 H3 histone pseudogene 16 Homo sapiens 86-89 7881906-7 1994 The presence of sulphate ions in the crystals and comparisons with the related Ha-ras-p21 oncogene product are used to infer the ATP-binding site, corroborated by the difference electron density for the ATP analogue AMP-PNP. Adenosine Triphosphate 203-206 H3 histone pseudogene 16 Homo sapiens 86-89 1731253-7 1992 We propose that recA protein may change its conformation upon ATP hydrolysis in a manner analogous to one such protein, the p21 protein from the ras oncogene. Adenosine Triphosphate 62-65 H3 histone pseudogene 16 Homo sapiens 124-127 2869483-0 1986 ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins. Adenosine Triphosphate 0-3 H3 histone pseudogene 16 Homo sapiens 96-99 2561364-1 1989 Purified membrane-bound Na,K-ATPase incubated with cobalt-tetrammine-ATP [Co(NH3)4ATP], which is a stable MgATP complex analog, shows two new types of membrane crystals, a new p21 form and a p4 form. Adenosine Triphosphate 106-111 H3 histone pseudogene 16 Homo sapiens 176-179 2869483-1 1986 The MgATP binding site of adenylate kinase, located by a combination of NMR and x-ray diffraction, is near three protein segments, five to seven amino acids in length, that are homologous in sequence to segments found in other nucleotide-binding phosphotransferases, such as myosin and F1-ATPase, ras p21 and transducin GTPases, and cAMP-dependent and src protein kinases, suggesting equivalent mechanistic roles of these segments in all of these proteins. Adenosine Triphosphate 4-9 H3 histone pseudogene 16 Homo sapiens 301-304 28494020-11 2017 Taken together, our results suggest that Panx3 modulates intracellular ATP levels, resulting in the inhibition of odontoblast proliferation through the AMPK/p21 signaling pathway and promotion of cell differentiation by the BMP/Smad signaling pathway. Adenosine Triphosphate 71-74 H3 histone pseudogene 16 Homo sapiens 157-160 31738805-0 2019 Phosphorylation-dependent activity-based conformational changes in P21-activated kinase family members and screening of novel ATP competitive inhibitors. Adenosine Triphosphate 126-129 H3 histone pseudogene 16 Homo sapiens 67-70 24289924-3 2014 We further show that cellular ATP level might act as a molecular switch for Thr55 phosphorylation on the p21 promoter, indicating that TAF1 is a cellular ATP sensor. Adenosine Triphosphate 30-33 H3 histone pseudogene 16 Homo sapiens 105-108 25482151-1 2014 BACKGROUND: PA28gamma (also known as Ki, REG gamma, PMSE3), a member of the ubiquitin-and ATP-independent proteasome activator family 11S, has been proved to show proteasome-dependent and -independent effects on several proteins including tumor suppressor p53, cyclin-dependent kinase inhibitor p21 and steroid receptor co-activator 3 (SCR-3). Adenosine Triphosphate 90-93 H3 histone pseudogene 16 Homo sapiens 295-298 24289924-3 2014 We further show that cellular ATP level might act as a molecular switch for Thr55 phosphorylation on the p21 promoter, indicating that TAF1 is a cellular ATP sensor. Adenosine Triphosphate 154-157 H3 histone pseudogene 16 Homo sapiens 105-108 24289924-4 2014 Upon DNA damage, cells undergo PARP-1-dependent ATP depletion, which is correlated with reduced TAF1 kinase activity and Thr55 phosphorylation, resulting in p21 activation. Adenosine Triphosphate 48-51 H3 histone pseudogene 16 Homo sapiens 157-160 22547681-8 2012 As a consequence, ATP levels increased, and the level of activity of the AMP-activated protein kinase (AMPK) declined, further contributing to the elevation in the abundance of p21. Adenosine Triphosphate 18-21 H3 histone pseudogene 16 Homo sapiens 177-180