PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
19748989-4	2009	Here, we show that extracellular ATP impairs in an IL-10-dependent fashion the expression of the tolerogenic soluble and membrane-bound HLA-G Ag in human monocytes.	Adenosine Triphosphate	33-36	interleukin 10	Homo sapiens	51-56	
21145936-11	2011	Moreover, ATP increased the production of the proinflammatory cytokines interleukin-2, interferon-gamma, and interleukin-12p70, while decreasing the anti-inflammatory cytokine interleukin-10, and this finding was associated with the reduced ability of MSCs to inhibit T-cell proliferation.	Adenosine Triphosphate	10-13	interleukin 10	Homo sapiens	176-190	
19748989-7	2009	Inhibition by ATP was reverted by supplementation of culture medium with exogenous IL-10.	Adenosine Triphosphate	14-17	interleukin 10	Homo sapiens	83-88	
19748989-8	2009	Due to the well-known immunosuppressive activity of IL-10 and soluble HLA-G, this novel effect of ATP might be relevant for the pathophysiology and therapy of inflammatory disorders.	Adenosine Triphosphate	98-101	interleukin 10	Homo sapiens	52-57	
18164682-4	2008	ATP inhibited radiation-induced TNF-alpha release and increased IL-10 release.	Adenosine Triphosphate	0-3	interleukin 10	Homo sapiens	64-69	
18472047-7	2008	Results showed that ATP decreased the rise in concentrations of TNF-alpha, interferon-gamma (IFN-gamma) and IL-1beta, but increased concentrations of IL-8 and IL-10.	Adenosine Triphosphate	20-23	interleukin 10	Homo sapiens	159-164	
16298759-4	2006	In the presence of H(2)O(2), ATP at concentrations of 100 and 300 microM inhibited Tumour Necrosis factor-alpha (TNF-alpha) release and stimulated IL-10 release in LPS-PHA stimulated whole blood.	Adenosine Triphosphate	29-32	interleukin 10	Homo sapiens	147-152	
17705579-10	2007	Our results suggest an association between low ATP and IL-10 concentrations and the presence of infection.	Adenosine Triphosphate	47-50	interleukin 10	Homo sapiens	55-60	
15719372-3	2005	The purpose of the present study was to determine the effects of ATP on TNF-alpha, IL-6 and IL-10 release in stimulated whole blood.	Adenosine Triphosphate	65-68	interleukin 10	Homo sapiens	92-97	
15719372-5	2005	Furthermore, these ATP concentrations induced an increase in IL-10 secretion by 48+/-5% and 62+/-7% in whole blood.	Adenosine Triphosphate	19-22	interleukin 10	Homo sapiens	61-66	
15719372-6	2005	The ATP analogue adenosine 5"-O-(3-thiotriphosphate) (ATP-gamma-S) and adenosine 5"-diphosphate (ADP) also inhibited TNF-alpha release, but only ADP showed a stimulatory effect on IL-10.	Adenosine Triphosphate	4-7	interleukin 10	Homo sapiens	180-185	
15719372-8	2005	These results show, for the first time, that ATP inhibits the inflammatory response in stimulated whole blood as indicated by inhibition of TNF-alpha and stimulation of IL-10 release and that this effect is predominantly mediated by ATP and not by adenosine.	Adenosine Triphosphate	45-48	interleukin 10	Homo sapiens	169-174	
11160202-5	2001	On the other hand, ATP markedly and dose-dependently inhibited LPS- and soluble CD40 ligand-dependent production of IL-1alpha, IL-1beta, TNF-alpha, IL-6, and IL-12, whereas IL-1 receptor antagonist and IL-10 production was not affected.	Adenosine Triphosphate	19-22	interleukin 10	Homo sapiens	202-207	
12626548-6	2003	TNF-alpha, IL-10, and IL-5 production showed intermediate sensitivity to these ATP analogs.	Adenosine Triphosphate	79-82	interleukin 10	Homo sapiens	11-16	
11160202-6	2001	As a result, T cell lines generated from allogeneic naive CD45RA(+) T cells primed with DCs matured in the presence of ATP produced lower amounts of IFN-gamma and higher levels of IL-4, IL-5, and IL-10 compared with T cell lines obtained with LPS-stimulated DCs.	Adenosine Triphosphate	119-122	interleukin 10	Homo sapiens	196-201	
34202215-10	2021	Our results suggest that ATP and TNF-alpha dominantly induce the physiological activities of 3 dpi neurons and microglia, and IL-10 effectively suppresses such changes of both activated cells in K+ channel- and P2 receptor-dependent manner, while IL-4 suppresses neurons preferentially.	Adenosine Triphosphate	25-28	interleukin 10	Homo sapiens	126-131	
26990545-7	2016	Production of IL-10 and expression of CD39 by CD8(+) T cells was independently regulated, being respectively blocked by extracellular ATP and enhanced by an A2A adenosine receptor agonist.	Adenosine Triphosphate	134-137	interleukin 10	Homo sapiens	14-19	
34175493-7	2022	However, ATP may also undergo catalysis by ectonucleotidases present in the parasite membrane, generating adenosine, which activates P1 receptors and induces the production of anti-inflammatory molecules such as prostaglandin E2 and IL-10.	Adenosine Triphosphate	9-12	interleukin 10	Homo sapiens	233-238	
32118580-7	2020	In (LPS/ATP-stimulated) PBMCs, IL-18/TNF/caspase-1 were all significantly decreased and IL-10 was increased with both combinations.	Adenosine Triphosphate	8-11	interleukin 10	Homo sapiens	88-93	
31911118-5	2020	The processes include the generation of "Find-Me" signals (such as adenosine triphosphate/uridine triphosphate, fractalkine, lysophosphatidylcholine, and sphingosine-1-phosphate) for the recruitment of viable macrophages, generation of the "Eat-Me" signals (for example, phosphatidylserine) for the engulfment process, and, finally, release of anti-inflammatory mediators (including transforming factor beta and interleukin-10) as a tolerance-enhancing and an anti-inflammatory response, and for the motile behavior of the apoptotic cell.	Adenosine Triphosphate	67-89	interleukin 10	Homo sapiens	412-426	
26435068-5	2017	In THP-1 cells, CORM-2 treatment dose-dependently reduced the activation of caspase-1 and the secretion of IL-1beta, and increased the levels of IL-10, in response to LPS and adenosine 5"-triphosphate (ATP), an NLRP3 inflammasome activation model.	Adenosine Triphosphate	175-200	interleukin 10	Homo sapiens	145-150	
32804985-7	2020	In addition to the effects of KW3110 on J774A.1 cells, KW3110 treatment induced IL-10 production in the supernatants of human monocytes, and KW3110 or IL-10 treatment suppressed caspase-1 activation and IL-1beta production in the supernatants of LPS/ATP-stimulated cells.	Adenosine Triphosphate	250-253	interleukin 10	Homo sapiens	151-156	
29031722-6	2017	IL10/TGFbeta-activated MPhis displayed high CD163 and low CD40 expression and secreted factors that decreased UQCRC2 gene/protein expression and ATP-linked respiration in human white adipocytes.	Adenosine Triphosphate	145-148	interleukin 10	Homo sapiens	0-4	
25458313-6	2015	Th cells cultured in the presence of supernatant derived from LPS/ATP inflammasome activated PBMC showed increased Th17 and GM-CSF+ Th17 cell frequencies in HC and MS patients and decreased anti-inflammatory IL-10+Th cell frequency in HC compared to Th cells cultured in the presence of control supernatant.	Adenosine Triphosphate	66-69	interleukin 10	Homo sapiens	208-213