PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21597914-2 2011 We tested whether secretin belonging to the glucagon/PACAP/VIP superfamily would increase transcription of the tyrosine hydroxylase (Th) gene and modulate catecholamine secretion. Catecholamines 155-168 vasoactive intestinal peptide Rattus norvegicus 59-62 21597914-6 2011 Secretin stimulated catecholamine secretion (EC(50) ~3.5 muM) from PC12 cells, but this was inhibited by pre-treatment with VIP-preferring receptor (VPAC1)/PACAP-preferring receptor (PAC1) antagonists. Catecholamines 20-33 vasoactive intestinal peptide Rattus norvegicus 124-127 10194528-1 1999 Previous studies, by this group and others, have shown that vasoactive intestinal peptide (VIP) stimulates aldosterone secretion, and that the actions of VIP on aldosterone secretion by the rat adrenal cortex are blocked by beta adrenergic antagonists, suggesting that VIP may act by the local release of catecholamines. Catecholamines 305-319 vasoactive intestinal peptide Rattus norvegicus 91-94 11641129-3 2001 The PACAP-induced catecholamine output responses were inhibited by the PACAP type I receptor antagonist PACAP- (6-38) (30-3,000 nM) but were resistant to the PACAP type II receptor antagonist [Lys1,Pro2,5,Ara3,4,Tyr6]-vasoactive intestinal peptide (LPAT-VIP; 30-3,000 nM). Catecholamines 18-31 vasoactive intestinal peptide Rattus norvegicus 254-257 12147212-1 2002 VIP and PACAP38 are closely related peptides that are released in the adrenal gland and sympathetic ganglia and regulate catecholamine synthesis and release. Catecholamines 121-134 vasoactive intestinal peptide Rattus norvegicus 0-3 10194528-1 1999 Previous studies, by this group and others, have shown that vasoactive intestinal peptide (VIP) stimulates aldosterone secretion, and that the actions of VIP on aldosterone secretion by the rat adrenal cortex are blocked by beta adrenergic antagonists, suggesting that VIP may act by the local release of catecholamines. Catecholamines 305-319 vasoactive intestinal peptide Rattus norvegicus 60-89 10194528-1 1999 Previous studies, by this group and others, have shown that vasoactive intestinal peptide (VIP) stimulates aldosterone secretion, and that the actions of VIP on aldosterone secretion by the rat adrenal cortex are blocked by beta adrenergic antagonists, suggesting that VIP may act by the local release of catecholamines. Catecholamines 305-319 vasoactive intestinal peptide Rattus norvegicus 154-157 10194528-1 1999 Previous studies, by this group and others, have shown that vasoactive intestinal peptide (VIP) stimulates aldosterone secretion, and that the actions of VIP on aldosterone secretion by the rat adrenal cortex are blocked by beta adrenergic antagonists, suggesting that VIP may act by the local release of catecholamines. Catecholamines 305-319 vasoactive intestinal peptide Rattus norvegicus 154-157 10194528-2 1999 The present studies were designed to test this hypothesis further, by measuring catecholamine release by adrenal capsular tissue in response to VIP stimulation. Catecholamines 80-93 vasoactive intestinal peptide Rattus norvegicus 144-147 10194528-11 1999 In the low sodium group VIP was found to increase catecholamine release to the same extent as in the control group, however, in contrast to the control group, the adrenal response to VIP was not altered by adrenergic antagonists in the low sodium group. Catecholamines 50-63 vasoactive intestinal peptide Rattus norvegicus 24-27 10194528-12 1999 These data provide strong support for the hypothesis that VIP acts by the local release of catecholamines in adrenal zona glomerulosa tissue in normal animals. Catecholamines 91-105 vasoactive intestinal peptide Rattus norvegicus 58-61 9466982-14 1998 The potent PACAP/vasoactive intestinal peptide (VIP) type I receptor antagonist PACAP6-38 impaired both chromogranin A transcription or catecholamine secretion triggered by PACAP38, while the PACAP/VIP type II receptor antagonist (p-Chloro-D-Phe6, Leu17)-VIP had little or no ability to antagonize the PACAP38 effect. Catecholamines 136-149 vasoactive intestinal peptide Rattus norvegicus 48-51 9466982-16 1998 Thus, PACAP-evoked chromogranin A transcription and catecholamine secretion are likely mediated by the PACAP/VIP type I receptor isoform. Catecholamines 52-65 vasoactive intestinal peptide Rattus norvegicus 109-112 9795163-1 1998 The actions of vasoactive intestinal polypeptide (VIP) on catecholamine secretion and changes in [Ca2+]i in single rat chromaffin cells were studied using amperometry and Indo-1. Catecholamines 58-71 vasoactive intestinal peptide Rattus norvegicus 15-48 9795163-1 1998 The actions of vasoactive intestinal polypeptide (VIP) on catecholamine secretion and changes in [Ca2+]i in single rat chromaffin cells were studied using amperometry and Indo-1. Catecholamines 58-71 vasoactive intestinal peptide Rattus norvegicus 50-53 9795163-12 1998 Thus in rat chromaffin cells, VIP acts both directly as a neurotransmitter in provoking sustained catecholamine secretion in a cAMP-independent manner, and also by enhancing ACh-induced secretion, via a cAMP-dependent action involving muscarinic receptors. Catecholamines 98-111 vasoactive intestinal peptide Rattus norvegicus 30-33 8006835-11 1994 Perfusion with VIP (10 microM for 4 min) resulted in the secretion of 27 ng of catecholamines and the ratio of adrenaline to noradrenaline was 9.7. Catecholamines 79-93 vasoactive intestinal peptide Rattus norvegicus 15-18 15001086-3 1997 Catecholamine release is similar to other species although it gives robust secretion in response to stimuli such as muscarinic agonists, bradykinin or VIP. Catecholamines 0-13 vasoactive intestinal peptide Rattus norvegicus 151-154 9809661-10 1998 VIP and PACAP raise aldosterone production via a paracrine indirect mechanism involving the stimulation of medullary chromaffin cells to release catecholamines, which in turn enhance the secretion of zona glomerulosa cells via a beta-adrenoceptor-mediated mechanism. Catecholamines 145-159 vasoactive intestinal peptide Rattus norvegicus 0-3 7491942-6 1995 These data led to the following conclusions: 1) PACAP was more potent than either carbachol or VIP in enhancing the secretion of catecholamine from the adrenal medulla, and 2) PACAP-induced catecholamine secretion was due to the direct action of PACAP on the adrenal medulla rather than an indirect action mediated by acetylcholine release. Catecholamines 129-142 vasoactive intestinal peptide Rattus norvegicus 95-98 7529068-12 1994 Colocalization of GAL or VIP with tyrosine hydroxylase (TH), the rate-limiting enzyme of catecholamine synthesis, reveals a reduced immunoreactivity for TH in intensely GAL- or VIP-positive cells, and vice versa at day 6. Catecholamines 89-102 vasoactive intestinal peptide Rattus norvegicus 25-28 7529068-12 1994 Colocalization of GAL or VIP with tyrosine hydroxylase (TH), the rate-limiting enzyme of catecholamine synthesis, reveals a reduced immunoreactivity for TH in intensely GAL- or VIP-positive cells, and vice versa at day 6. Catecholamines 89-102 vasoactive intestinal peptide Rattus norvegicus 177-180 8006835-12 1994 A higher concentration of VIP (20 microM for 4 min) resulted in the secretion of greater amounts of catecholamines (102 ng) without significantly altering the ratio of adrenaline to noradrenaline (10.9). Catecholamines 100-114 vasoactive intestinal peptide Rattus norvegicus 26-29 7910672-6 1994 A most intriguing property of rat chromaffin cells is that stimulation of nicotinic, muscarinic, VIP or PACAP receptors are each able to produce robust catecholamine secretion on their own. Catecholamines 152-165 vasoactive intestinal peptide Rattus norvegicus 97-100 7910672-9 1994 We demonstrate that acetylcholine, nicotine, muscarine, VIP and PACAP are each able to evoke catecholamine secretion from a single chromaffin cell. Catecholamines 93-106 vasoactive intestinal peptide Rattus norvegicus 56-59 1688031-0 1991 The peptide VIP is a neurotransmitter in rat adrenal medulla: physiological role in controlling catecholamine secretion. Catecholamines 96-109 vasoactive intestinal peptide Rattus norvegicus 12-15 8190350-0 1994 Neuropeptide Y (NPY)- and vasoactive intestinal peptide (VIP)-induced aldosterone secretion by rat capsule/glomerular zone could be mediated by catecholamines via beta 1 adrenergic receptors. Catecholamines 144-158 vasoactive intestinal peptide Rattus norvegicus 57-60 8190350-3 1994 The two NPY analogs as well as the VIP stimulated the release of catecholamines and of aldosterone. Catecholamines 65-79 vasoactive intestinal peptide Rattus norvegicus 35-38 1289063-4 1992 When assayed on cultured rat sympathetic neurons, the major activities in footpad extracts from postnatal day 21 rat pups that induce choline acetyltransferase (ChAT) and vasoactive intestinal peptide (VIP) and reduce catecholamines and neuropeptide Y (NPY) are associated with a soluble protein of 22-26 x 10(3) M(r) and a pI of 5.0. Catecholamines 218-232 vasoactive intestinal peptide Rattus norvegicus 202-205 1613427-0 1992 Vasoactive intestinal peptide stimulation of aldosterone secretion by the rat adrenal cortex may be mediated by the local release of catecholamines. Catecholamines 133-147 vasoactive intestinal peptide Rattus norvegicus 0-29 1688031-20 1991 The VIP receptor antagonist inhibited VIP-evoked secretion of catecholamines without affecting ACh-evoked secretion. Catecholamines 62-76 vasoactive intestinal peptide Rattus norvegicus 4-7 1688031-20 1991 The VIP receptor antagonist inhibited VIP-evoked secretion of catecholamines without affecting ACh-evoked secretion. Catecholamines 62-76 vasoactive intestinal peptide Rattus norvegicus 38-41 3123488-0 1988 Vasoactive intestinal polypeptide and muscarine mobilize intracellular Ca2+ through breakdown of phosphoinositides to induce catecholamine secretion. Catecholamines 125-138 vasoactive intestinal peptide Rattus norvegicus 0-33 2170629-15 1990 Vasoactive intestinal polypeptide (VIP) and muscarine induced catecholamine secretion from the perfused adrenal medulla via formation of inositol-1,4,5-tirisphosphate (IP3). Catecholamines 62-75 vasoactive intestinal peptide Rattus norvegicus 0-33 2170629-15 1990 Vasoactive intestinal polypeptide (VIP) and muscarine induced catecholamine secretion from the perfused adrenal medulla via formation of inositol-1,4,5-tirisphosphate (IP3). Catecholamines 62-75 vasoactive intestinal peptide Rattus norvegicus 35-38 2470585-6 1989 These findings strengthen the assumption that VIP controls glucose and fatty acid metabolism by a cAMP-dependent mechanism and demonstrate, for the first time, that the contribution of substrates as energy fuel is under dual neurohormonal regulation by VIP and catecholamines in isolated rat enterocytes. Catecholamines 261-275 vasoactive intestinal peptide Rattus norvegicus 46-49 2556506-0 1989 Cross-communication between acetylcholine and VIP in controlling catecholamine secretion by affecting cAMP, inositol triphosphate, protein kinase C, and calcium in rat adrenal medulla. Catecholamines 65-78 vasoactive intestinal peptide Rattus norvegicus 46-49 3123488-2 1988 We have recently shown that vasoactive intestinal polypeptide (VIP) is as potent as acetylcholine in inducing the secretion of catecholamines from the rat adrenal medulla. Catecholamines 127-141 vasoactive intestinal peptide Rattus norvegicus 28-61 3123488-2 1988 We have recently shown that vasoactive intestinal polypeptide (VIP) is as potent as acetylcholine in inducing the secretion of catecholamines from the rat adrenal medulla. Catecholamines 127-141 vasoactive intestinal peptide Rattus norvegicus 63-66 3123488-3 1988 In the present study we have investigated the molecular mechanism involved in the exocytotic secretion of catecholamines by VIP and the effects of VIP on Ca45 uptake and phosphoinositide breakdown and compared them with those of the classical cholinergic agonists. Catecholamines 106-120 vasoactive intestinal peptide Rattus norvegicus 124-127 3656194-0 1987 Vasoactive intestinal polypeptide stimulates the secretion of catecholamines from the rat adrenal gland. Catecholamines 62-76 vasoactive intestinal peptide Rattus norvegicus 0-33 3040005-4 1987 These results raise the possibility that cGMP accumulation in other tissues might be regulated by VIP, and that the stimulating effects of VIP might be markedly amplified by catecholamine transmitters in these tissues. Catecholamines 174-187 vasoactive intestinal peptide Rattus norvegicus 139-142 3656194-10 1987 0.3 microM-VIP caused a significant increase in the secretion of catecholamines, and the effect increased with an increase in the concentration of VIP. Catecholamines 65-79 vasoactive intestinal peptide Rattus norvegicus 11-14 3656194-10 1987 0.3 microM-VIP caused a significant increase in the secretion of catecholamines, and the effect increased with an increase in the concentration of VIP. Catecholamines 65-79 vasoactive intestinal peptide Rattus norvegicus 147-150 3656194-11 1987 About 115 ng of catecholamines were secreted during 15 min perfusion with 3 microM-VIP. Catecholamines 16-30 vasoactive intestinal peptide Rattus norvegicus 83-86 3656194-18 1987 It is suggested that VIP may be the non-cholinergic excitatory substance present in the splanchnic nerves and released along with acetylcholine during simulation of the nerves to evoke secretion of catecholamine from the rat chromaffin cells. Catecholamines 198-211 vasoactive intestinal peptide Rattus norvegicus 21-24 6180787-4 1982 The catecholamine modulation of the intrinsic rhythmical contractions of the portal vein may be complemented by SP released from intramural nerves and VIP released from the adventitial nerves. Catecholamines 4-17 vasoactive intestinal peptide Rattus norvegicus 151-154 2867499-5 1985 Nerve fibers containing VIP-like immunoreactive material have been reported in the adrenal medulla and in other catecholamine (CA)- storing tissues. Catecholamines 112-125 vasoactive intestinal peptide Rattus norvegicus 24-27 33220286-9 2021 The blocking of VIP signaling produces changes in ovarian catecholamines. Catecholamines 58-72 vasoactive intestinal peptide Rattus norvegicus 16-19