PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2223810-9 1990 Although chromaffin granule ghost-associated phospholipase A2 is most likely a lysosomal contaminant, its broad, biomembrane-modulated pH range may still allow it to participate in catecholamine secretion. Catecholamines 181-194 LOC104974671 Bos taurus 45-61 6865904-0 1983 Phospholipase A2 inhibitors block catecholamine secretion and calcium uptake in cultured bovine adrenal medullary cells. Catecholamines 34-47 LOC104974671 Bos taurus 0-16 6865904-2 1983 The possibility that it may be involved in exocytosis of catecholamine from primary dissociated cultures of bovine adrenal medullary cells was investigated by studying the effects on catecholamine secretion and 44Ca2+ uptake of three phospholipase A2 inhibitors: p-bromophenacyl bromide (BPB), Upjohn Compound 1002, and mepacrine. Catecholamines 57-70 LOC104974671 Bos taurus 234-250 6865904-10 1983 The data suggest that phospholipase A2 inhibitors block catecholamine secretion from intact chromaffin cells by blocking Ca2+ influx. Catecholamines 56-69 LOC104974671 Bos taurus 22-38 1335253-2 1992 In the present study, we examined the relationship between phospholipase A2 and C activation and catecholamine secretion by PGE2 in chromaffin cells. Catecholamines 97-110 LOC104974671 Bos taurus 59-75 1335253-3 1992 The phospholipase A2 inhibitors p-bromophenacyl bromide and mepacrine did not affect the basal and ouabain-induced release, but dose-dependently blocked PGE2-evoked phosphoinositide metabolism and the consequent catecholamine release at an IC50 value of 3 microM. Catecholamines 212-225 LOC104974671 Bos taurus 4-20 6847709-0 1983 Suppression by phospholipase A2 inhibitors of secretion of catecholamines from isolated adrenal medullary cells by suppression of cellular calcium uptake. Catecholamines 59-73 LOC104974671 Bos taurus 15-31 6847709-1 1983 The involvement of phospholipase A2 in the secretion of catecholamines and cellular uptake of 45Ca2+ was investigated in isolated bovine adrenal medullary cells. Catecholamines 56-70 LOC104974671 Bos taurus 19-35 6847709-3 1983 Phospholipase A2 inhibitors, such as quinacrine, chloroquine, quinine and p-bromophenacyl bromide, all inhibited the secretion of catecholamines evoked by carbamylcholine in a dose-dependent manner. Catecholamines 130-144 LOC104974671 Bos taurus 0-16 6847709-4 1983 These phospholipase A2 inhibitors also inhibited the cellular uptake of 45Ca2+ evoked by carbamylcholine with similar dose-response curves to those for inhibition of catecholamine secretion. Catecholamines 166-179 LOC104974671 Bos taurus 6-22 6847709-6 1983 Phospholipase A2 inhibitors seem to suppress the secretion of catecholamines by interfering with the linkage between acetylcholine receptors and Ca-channels by the membrane effects including the inhibition of endogenous phospholipase A2 activity of the adrenal medullary cells. Catecholamines 62-76 LOC104974671 Bos taurus 0-16 6847709-6 1983 Phospholipase A2 inhibitors seem to suppress the secretion of catecholamines by interfering with the linkage between acetylcholine receptors and Ca-channels by the membrane effects including the inhibition of endogenous phospholipase A2 activity of the adrenal medullary cells. Catecholamines 62-76 LOC104974671 Bos taurus 220-236