PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12047348-1 2002 BACKGROUND: Aromatic L-amino acid decarboxylase (AADC) is the enzyme responsible for the decarboxylation step in both the catecholamine and indoleamine synthetic pathways. Catecholamines 122-135 dopa decarboxylase Rattus norvegicus 12-47 20407462-1 2011 The catecholamine, dopamine (DA), is synthesized from 3,4-dihydroxy-L-phenylalanine (L-DOPA) by aromatic L-amino acid decarboxylase (AADC). Catecholamines 4-17 dopa decarboxylase Rattus norvegicus 105-131 20407462-1 2011 The catecholamine, dopamine (DA), is synthesized from 3,4-dihydroxy-L-phenylalanine (L-DOPA) by aromatic L-amino acid decarboxylase (AADC). Catecholamines 4-17 dopa decarboxylase Rattus norvegicus 133-137 12047348-1 2002 BACKGROUND: Aromatic L-amino acid decarboxylase (AADC) is the enzyme responsible for the decarboxylation step in both the catecholamine and indoleamine synthetic pathways. Catecholamines 122-135 dopa decarboxylase Rattus norvegicus 49-53 9591841-1 1998 Tyrosine hydroxylase of catecholamine neurons catalyzes the synthesis of 3,4-dihydroxphenylalanine (DOPA), which is subsequently metabolized to dopamine by DOPA decarboxylase (DDC). Catecholamines 24-37 dopa decarboxylase Rattus norvegicus 156-174 11173223-2 2001 Immunoreactivity for the catecholamine biosynthetic enzymes tyrosine hydroxylase (TH), aromatic-L-amino-acid decarboxylase (AADC) and dopamine beta-hydroxylase (DBH) was present in all chromaffin cells, while phenylethanolamine N-methyltransferase (PNMT) was used to determine adrenergic chromaffin cell groups. Catecholamines 25-38 dopa decarboxylase Rattus norvegicus 87-122 11173223-2 2001 Immunoreactivity for the catecholamine biosynthetic enzymes tyrosine hydroxylase (TH), aromatic-L-amino-acid decarboxylase (AADC) and dopamine beta-hydroxylase (DBH) was present in all chromaffin cells, while phenylethanolamine N-methyltransferase (PNMT) was used to determine adrenergic chromaffin cell groups. Catecholamines 25-38 dopa decarboxylase Rattus norvegicus 124-128 9591841-1 1998 Tyrosine hydroxylase of catecholamine neurons catalyzes the synthesis of 3,4-dihydroxphenylalanine (DOPA), which is subsequently metabolized to dopamine by DOPA decarboxylase (DDC). Catecholamines 24-37 dopa decarboxylase Rattus norvegicus 176-179 1465439-1 1992 Aromatic L-amino acid decarboxylase (AADC, EC 4.1.1.28) catalyzes the decarboxylation of L-dopa to dopamine in catecholamine cells and 5-hydroxytryptophan to serotonin in serotonin-producing neurons. Catecholamines 111-124 dopa decarboxylase Rattus norvegicus 0-35 9349551-3 1997 We compared catecholamine synthesis in vitro in cultures of cells with tyrosine hydroxylase and aromatic L-amino acid decarboxylase together versus cocultures of cells containing these enzymes separately. Catecholamines 12-25 dopa decarboxylase Rattus norvegicus 96-131 9137906-5 1997 As DDC is an enzyme specifically involved in catecholamine synthesis, insular cells must possess the capacity to elaborate this class of hormone at least up to the dopamine-decarboxylation step. Catecholamines 45-58 dopa decarboxylase Rattus norvegicus 3-6 9057138-8 1997 This study introduces novel results with regard to the regulation of the gene expression of AADC in PC12 cells, which is not paralleled by the other catecholamine biosynthetic enzymes. Catecholamines 149-162 dopa decarboxylase Rattus norvegicus 92-96 9043712-1 1997 HPLC and Palkovits" microdissection technique were used to measure activities of two catecholamine-synthesizing enzymes, tyrosine hydroxylase (TH) and dopa decarboxylase (DD), in the medial preoptic area (MPA) and arcuate nucleus (AN), both of which are involved in LH regulation. Catecholamines 85-98 dopa decarboxylase Rattus norvegicus 151-169 7595477-2 1995 We have analyzed the expression of the neuronal promoter of the AADC gene in cells synthesizing catecholamines and serotonin, as well as in non-AADC-expressing cells. Catecholamines 96-110 dopa decarboxylase Rattus norvegicus 64-68 1465439-1 1992 Aromatic L-amino acid decarboxylase (AADC, EC 4.1.1.28) catalyzes the decarboxylation of L-dopa to dopamine in catecholamine cells and 5-hydroxytryptophan to serotonin in serotonin-producing neurons. Catecholamines 111-124 dopa decarboxylase Rattus norvegicus 37-41 3011767-8 1986 Although the physiological role of RSP-V has not yet been clarified, this enzyme inactivated dopa decarboxylase alone among catecholamine-synthesizing enzymes. Catecholamines 124-137 dopa decarboxylase Rattus norvegicus 93-111 2813383-0 1989 Molecular cloning and sequencing of a cDNA of rat dopa decarboxylase: partial amino acid homologies with other enzymes synthesizing catecholamines. Catecholamines 132-146 dopa decarboxylase Rattus norvegicus 50-68 2813383-6 1989 A sequence of 58 amino acid residues, including this repeating structure of rat DDC, was found to show homologies with those of rat tyrosine hydroxylase, human dopamine beta-hydroxylase, and bovine phenylethanolamine N-methyltransferase, other mammalian enzymes that synthesize catecholamines. Catecholamines 278-292 dopa decarboxylase Rattus norvegicus 80-83 2518613-6 1989 To confirm the validity of these results, specific antibodies to tyrosine hydroxylase (TH) and aromatic 1-aminoacid-decarboxylase (AADC), two enzymes involved in the synthesis of catecholamines, were used. Catecholamines 179-193 dopa decarboxylase Rattus norvegicus 131-135 3110796-8 1987 These results indicate that changes in the metabolic pathways of splenic catecholamines occur at the peak of the clinical symptoms of EAE; the increase in DOPA and the decrease in DA concentrations suggest that the activity of DOPA-decarboxylase or its co-factor is altered. Catecholamines 73-87 dopa decarboxylase Rattus norvegicus 227-245 2429074-9 1986 was prevented by pretreatment with propranolol, desmethylimipramine, and the dopa-decarboxylase inhibitor R04-4602, but not by pretreatment with pentolinium, guanethidine, the dopamine-beta-hydroxylase inhibitor FLA-63, or by adrenalectomy or depletion of endogenous catecholamines. Catecholamines 267-281 dopa decarboxylase Rattus norvegicus 77-95 5922312-0 1966 The influence of the dopa decarboxylase inhibitor Ro4-4602 on the urinary excretion of catecholamines in cold-stressed rats. Catecholamines 87-101 dopa decarboxylase Rattus norvegicus 21-39 30651588-4 2019 In the adrenal glands of prehypertensive SHR, the expression of catecholamine biosynthetic enzymes Ddc, Dbh and Pnmt was lower than in aged-matched Wistar-Kyoto rats. Catecholamines 64-77 dopa decarboxylase Rattus norvegicus 99-102 30651588-6 2019 In the adrenal glands of adult SHR, the expression of catecholamine biosynthetic enzymes Th, Ddc, Dbh and Pnmt was decreased along the amounts of dopamine and noradrenaline (50% and 38%, respectively, p < 0.001). Catecholamines 54-67 dopa decarboxylase Rattus norvegicus 93-96 6371583-4 1984 Aromatic L-amino acid decarboxylase was also present in serotonin neurons and the majority of catecholamine cell groups. Catecholamines 94-107 dopa decarboxylase Rattus norvegicus 0-35