PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16643958-6 2006 The remarkable increases in levels of expression of tyrosine hydroxylase, DOPA decarboxylase and dopamine beta-hydroxylase suggest that MK together with PTN are very important regulators of the catecholamine pathway in mouse aorta and may critically regulate catecholamine biosynthesis and function in inflammatory and the other pathological conditions in which Mk or Ptn are upregulated. Catecholamines 194-207 pleiotrophin Mus musculus 153-156 15985215-2 2005 The Mk and Ptn genes are essential for normal development of the catecholamine and renin-angiotensin pathways and the synthesis of different collagens. Catecholamines 65-78 pleiotrophin Mus musculus 11-14 15369781-0 2004 Pleiotrophin is a major regulator of the catecholamine biosynthesis pathway in mouse aorta. Catecholamines 41-54 pleiotrophin Mus musculus 0-12 15369781-4 2004 These findings suggest that Ptn gene expression has a critical role in determining the levels of expression of the enzymes of catecholamine biosynthesis in aorta and through this mechanism, PTN may regulate levels of endogenous catecholamine synthesis and potentially the vascular tone of aorta. Catecholamines 126-139 pleiotrophin Mus musculus 28-31 15369781-4 2004 These findings suggest that Ptn gene expression has a critical role in determining the levels of expression of the enzymes of catecholamine biosynthesis in aorta and through this mechanism, PTN may regulate levels of endogenous catecholamine synthesis and potentially the vascular tone of aorta. Catecholamines 126-139 pleiotrophin Mus musculus 190-193 15369781-4 2004 These findings suggest that Ptn gene expression has a critical role in determining the levels of expression of the enzymes of catecholamine biosynthesis in aorta and through this mechanism, PTN may regulate levels of endogenous catecholamine synthesis and potentially the vascular tone of aorta. Catecholamines 228-241 pleiotrophin Mus musculus 28-31 15369781-4 2004 These findings suggest that Ptn gene expression has a critical role in determining the levels of expression of the enzymes of catecholamine biosynthesis in aorta and through this mechanism, PTN may regulate levels of endogenous catecholamine synthesis and potentially the vascular tone of aorta. Catecholamines 228-241 pleiotrophin Mus musculus 190-193