PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22109853-5 2012 We also demonstrated that tyrosine hydroxylase (TH), the rate-limiting enzyme for synthesis of catecholamine, was reduced after exposure to IL-6, which was accompanied by JAK-STAT3 pathway activation. Catecholamines 95-108 signal transducer and activator of transcription 3 Homo sapiens 175-180 25798840-6 2016 Catecholamine stimulation upregulates the expression of miR-21 and MUC-1 by activating Her2 and STAT3, leading to deficiency of phosphatase and tensin homolog and activation of phosphatidylinositol-3-kinase (PI3K) and Akt. Catecholamines 0-13 signal transducer and activator of transcription 3 Homo sapiens 96-101 23630346-6 2013 Mechanistically, catecholamine induced upregulation of the MUC4 expression at both transcription and protein levels via activating STAT3 and ERK. Catecholamines 17-30 signal transducer and activator of transcription 3 Homo sapiens 131-136 20939893-0 2010 Catecholamine up-regulates MMP-7 expression by activating AP-1 and STAT3 in gastric cancer. Catecholamines 0-13 signal transducer and activator of transcription 3 Homo sapiens 67-72