PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29649477-6 2018 Considering that prostatic catecholamine overactivity serves as an essential etiology of pelvic pain by indirectly stimulating the smooth muscle cell proliferation, or by directly causing muscular spasm, our results collectively suggest that targeting the NF-kappaB, HIF-1alpha and HDACs pathways in prostate ICCs be considered as a new strategy for treatment of chronic pelvic pain syndrome (CPPS) induced by chronic prostatitis (CP). Catecholamines 27-40 hypoxia inducible factor 1, alpha subunit Mus musculus 267-277 15843612-1 2005 Hypoxia-inducible factor-1alpha (HIF-1alpha) plays an essential role in cellular and systemic O(2) homeostasis by regulating the expression of genes important in glycolysis, erythropoiesis, angiogenesis, and catecholamine metabolism. Catecholamines 208-221 hypoxia inducible factor 1, alpha subunit Mus musculus 0-31 15843612-1 2005 Hypoxia-inducible factor-1alpha (HIF-1alpha) plays an essential role in cellular and systemic O(2) homeostasis by regulating the expression of genes important in glycolysis, erythropoiesis, angiogenesis, and catecholamine metabolism. Catecholamines 208-221 hypoxia inducible factor 1, alpha subunit Mus musculus 33-43