PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11801260-4 2002 Stress, by activating the sympathetic nervous system, the hypothalamic-pituitary axis, and the renin-angiotensin system, causes the release of various stress hormones such as catecholamines, corticosteroids, glucagon, growth hormone, and renin, and elevated levels of homocysteine, which induce a heightened state of cardiovascular activity, injured endothelium, and induction of adhesion molecules on endothelial cells to which recruited inflammatory cells adhere and translocate to the arterial wall. Catecholamines 175-189 renin Homo sapiens 95-100 12847574-1 2000 This review describes the pharmacological aspects of renin release with special emphasis on the role of sympathetic nervous system, catecholamines, adrenoceptor blocking drugs, humoral agents, adrenalectomy and chemical sympathectomy. Catecholamines 132-146 renin Homo sapiens 53-58 11208687-13 2001 CONCLUSIONS: -Our data suggest that salt-depleted salt-sensitive hypertensives with blunted renin responses exhibit enhanced catecholamine-stimulated endothelin levels and may therefore respond better than unselected patients with essential hypertension to endothelin receptor blockers. Catecholamines 125-138 renin Homo sapiens 92-97 1509494-4 1992 The observation of high blood pressure and elevated levels of renin suggests that in addition to increased circulating catecholamines following scorpion envenomation, sympathetically induced renin release may play an important role in the pathogenesis of hypertension. Catecholamines 119-133 renin Homo sapiens 62-67 9453523-12 1998 Unlike patients with cardioinhibitory syncope, the renin-angiotensin-aldosterone axis is activated in patients with vasodepressor syncope and patients with a negative result of head-up tilt test without a statistically significant increase in catecholamine levels. Catecholamines 243-256 renin Homo sapiens 51-56 8677205-12 1996 CONCLUSIONS: Hypertension and family history of it changes adrenergic reactivity and influences the relationship between plasma renin activity, aldosterone, and catecholamines. Catecholamines 161-175 renin Homo sapiens 128-133 7674267-2 1995 Thus, diuretics stimulate the renin angiotensin and catecholamine systems and, in some cases, vasopressin. Catecholamines 52-65 renin Homo sapiens 30-35 1473654-8 1992 CONCLUSIONS: The relationship between the renin angiotensin system and catecholamines is complex but our findings indicate that: 1) Traditional therapy is effective in improving symptoms, but cannot induce a decrease of vasoconstrictive neurohormones; 2) ACE inhibitor therapy reduces ANF and neurohormonal activation. Catecholamines 71-85 renin Homo sapiens 42-47 9429845-6 1997 We argue that the beneficial effects are, at least in part, related to a reduction in the direct toxic effects of angiotensin II and catecholamines on cardiomyocytes resulting from the long term excess stimulation of the renin-angiotensin and sympathetic systems in these patients. Catecholamines 133-147 renin Homo sapiens 221-226 1488334-2 1992 It was found, that captopril in hypertensive patients with high plasma renin activity decreases both systolic and diastolic blood pressure, decelerates heart rate, and decreases serum total catecholamines and plasma renin activity. Catecholamines 190-204 renin Homo sapiens 71-76 2473355-3 1989 In these studies and other high dose constant infusion experiments, the response of the renin-angiotension-aldosterone system and plasma catecholamines was varied, either remaining unchanged or showing stimulation when high doses of ANF caused acute and substantial falls in blood pressure. Catecholamines 137-151 renin Homo sapiens 88-93 2483424-6 1989 The synthesis of renin is initiated when the cAMP concentration increases under the influence of hormones (parathyroid hormone, catecholamines), of mediators (e.g., prostanoids), or of changes in composition of tubular fluid (in sodium, chlorine, or calcium) detected by the macula densa. Catecholamines 128-142 renin Homo sapiens 17-22 1535395-5 1992 There were higher positive correlations between the levels of natural natriuretic factor and those of hormones of the renin-angiotensin-aldosterone system and catecholamines in patients having a diastolic pressure of greater than 115 mm Hg. Catecholamines 159-173 renin Homo sapiens 118-123 1810694-1 1991 During three consecutive days of prazosin treatment in a patient with pheochromocytoma, urinary catecholamine metabolite levels were correlated with plasma renin activity. Catecholamines 96-109 renin Homo sapiens 156-161 1810694-3 1991 This suggests that prazosin may interrupt the vicious cycle of worsening hypertension provoked by further activation of the renin-angiotensin system mediated by excessive circulating catecholamines. Catecholamines 183-197 renin Homo sapiens 124-129 2184065-0 1990 The activity of the renin-angiotensin-aldosterone system before and during submaximal bicycle exercise in relation to circulatory catecholamines in patients with type 1 (insulin-dependent) diabetes mellitus. Catecholamines 130-144 renin Homo sapiens 20-25 2192824-0 1990 Relationship between plasma catecholamines and the renin-aldosterone system during exercise in normal and essential hypertensive subjects. Catecholamines 28-42 renin Homo sapiens 51-56 3675477-2 1987 The specific feature of adaptation to this exposure is the transition to a new level of hormonal regulation with a significant increase of the content (production) of glucocorticoids, catecholamines, components of the renin-angiotensin-aldosterone system, which determines a modified activity of tissue hormones, and fluid-electrolyte homeostasis, as well as simultaneous increase of insulin secretion that diminishes the metabolic effects of glucocorticoids and catecholamines. Catecholamines 463-477 renin Homo sapiens 218-223 2905474-3 1988 This holds for the following neuro-endocrine mechanisms: 1) increased activity of the sympathetic nervous system and high plasma catecholamines, accompanied by down-regulation of beta 1- but not beta 2-receptors in the heart; 2) stimulation of the renin-angiotensin-aldosterone system (RAAS), causing higher levels of renin, A II and aldosterone. Catecholamines 129-143 renin Homo sapiens 248-253 2853087-8 1988 The increase of plasma renin activity, in turn, is attributable both to the increased catecholamine concentrations and to the decreased potassium levels. Catecholamines 86-99 renin Homo sapiens 23-28 6341193-5 1983 In pheochromocytoma, high levels of plasma catecholamines contribute to a high renin state which may have pathophysiologic implications. Catecholamines 43-57 renin Homo sapiens 79-84 3514428-7 1986 Direct stimulation of renin-containing cells by catecholamines is suggested as the cause of the hyperplasia. Catecholamines 48-62 renin Homo sapiens 22-27 3512264-10 1986 The association after swimming compared to running of a decreased PRA and an enhanced catecholamine response rule out a strict dependence of renin release under the effect of plasma catecholamines and is evidence of the major role of neural pathways for renin secretion during physical exercise. Catecholamines 86-99 renin Homo sapiens 254-259 6378438-0 1984 Supine and standing plasma catecholamines in essential hypertensive patients with different renin levels. Catecholamines 27-41 renin Homo sapiens 92-97 6681179-8 1983 Renin release is, at least in part, controlled by circulating catecholamines. Catecholamines 62-76 renin Homo sapiens 0-5 6350003-5 1983 A close correlation was found between urine catecholamines and plasma renin activity and between urine noradrenaline and aldosterone. Catecholamines 44-58 renin Homo sapiens 70-75 6282185-1 1982 Sympathetic outflow influences the renal release of renin through modifications of the tonic activity of the renal nerves and the plasma concentration of catecholamines. Catecholamines 154-168 renin Homo sapiens 52-57 6271155-1 1981 1 Relationship between plasma catecholamines (measured as noradrenaline and adrenaline) and plasma renin activity (PRA) were examined at rest and during passive head-up tilting for 30 min in nine normal subjects, before and after treatment with propranolol 160 mg daily for 7 days. Catecholamines 30-44 renin Homo sapiens 99-104 7044409-5 1982 The decreased activity of the renin-aldosterone axis after administration of L-dopa may be attributed to an accumulation of dopamine and catecholamines in the brain, resulting in a diminution of sympathetic outflow from the central nervous system. Catecholamines 137-151 renin Homo sapiens 30-35 7002344-0 1980 The role of the renin-angiotensin system in mediation of adrenal catecholamine secretion in the cat induced by intrarenal beta-adrenergic stimulation. Catecholamines 65-78 renin Homo sapiens 16-21 7002344-1 1980 Isoproterenol infusion (0.1 microgram/kg per min) into the renal artery of the cat induced an increase in plasma renin concentration (PRC) from 14.3 +/- 5.7 (mean +/- SE) ng angiotensin I/ml per hr to 56.8 +/- 7.7 after 70 minutes (P < 0.05) and an increase in catecholamine secretion rate from 38.7 +/- 6.0 ng/kg per 10 min to 180.0 +/- 40.0 after 70 minutes (P < 0.001). Catecholamines 264-277 renin Homo sapiens 113-118 7004717-9 1980 Increased activity of the renin-angiotensin and adrenergic nervous systems evoked by stressful stimuli enhances prostaglandin synthesis, which protects organ function from excessive effects of angiotensins and catecholamines. Catecholamines 210-224 renin Homo sapiens 26-31 7010196-5 1980 There were also higher levels of urinary catecholamines in the high renin group of patients. Catecholamines 41-55 renin Homo sapiens 68-73 6986474-7 1980 The mechanism directing elevated renin secretion may be related to changes in regional blood flow in addition to the stimulus of increased catecholamine activity. Catecholamines 139-152 renin Homo sapiens 33-38 998517-0 1976 Increased plasma catecholamines in high renin hypertension. Catecholamines 17-31 renin Homo sapiens 40-45 639332-7 1978 Many factors may be involved in the increased activation of the renin-angiotensin-aldosterone system: low blood pressure, hypersensitivity of the macula densa to catecholamines, relative insensitivity of the immature kidney to aldosterone, hyperkalaemia and other control mechanisms for aldosterone secretion all of which probably operate simultaneously during the first days of life. Catecholamines 162-176 renin Homo sapiens 64-69 624999-13 1978 These findings provide further support for the view that the process of catecholamine-induced renin secretion involves mobilization of Ca from a cellular site. Catecholamines 72-85 renin Homo sapiens 94-99 865132-1 1977 We found increased levels of catecholamines in some patients who had high-renin hypertension. Catecholamines 29-43 renin Homo sapiens 74-79 998517-2 1976 Seventy percent of hypertensive patients with high renin levels had increased catecholamines compared with a 14% incidence in the combined group with low and normal renin (P less than 0.001). Catecholamines 78-92 renin Homo sapiens 51-56 998517-3 1976 Basal catecholamines were related directly to renin in the hypertensive patients and to blood pressure in the normal (P less than 0.05), but not in the high and low renin subgroups, and inversely to percent increase of catecholamines after standing plus furosemide in hypertensive and normotensive patients (P less than 0.01). Catecholamines 7-21 renin Homo sapiens 47-52 999213-6 1976 Plasma renin activity values correlated positively with 12-hour urinary VMA excretion (p less than 0.01) and negatively with 6-hour urinary sodium excretion (p less than 0.05) before and after Sauna, suggesting the role of catecholamines and sodium depletion in renin response in Sauna. Catecholamines 223-237 renin Homo sapiens 7-12 976208-0 1976 Relationship between plasma renin activity and urinary catecholamines in various types of hypertension. Catecholamines 55-69 renin Homo sapiens 28-33 976208-9 1976 It thus appears that endogenous catecholamines, first of all the ratio between the renin-inhibiting DA and the renin-stimulating NA, participate as one of several factors in the regulation of secretion and of the plasma levels of renin not only in juvenile hypertensive patients with hyperkinetic circulation but also in other types of hypertension. Catecholamines 32-46 renin Homo sapiens 83-88 976208-9 1976 It thus appears that endogenous catecholamines, first of all the ratio between the renin-inhibiting DA and the renin-stimulating NA, participate as one of several factors in the regulation of secretion and of the plasma levels of renin not only in juvenile hypertensive patients with hyperkinetic circulation but also in other types of hypertension. Catecholamines 32-46 renin Homo sapiens 111-116 976208-9 1976 It thus appears that endogenous catecholamines, first of all the ratio between the renin-inhibiting DA and the renin-stimulating NA, participate as one of several factors in the regulation of secretion and of the plasma levels of renin not only in juvenile hypertensive patients with hyperkinetic circulation but also in other types of hypertension. Catecholamines 32-46 renin Homo sapiens 111-116 14500-7 1976 The results indicate that augmentation in renin release depends on the ratio of the different catecholamines secreted by the pheochromocytoma and their different effe-tiveness in stimulating beta-adrenergic receptors. Catecholamines 94-108 renin Homo sapiens 42-47 14500-9 1976 Normalization of catecholamine-induced enhanced renin release in patients with pheochromocytoma during chronic alpha-adrenergic receptor blockade supports the assumption that (alpha-) adrenergic blocking agents inhibit renin secretion distal to their blockade of specific adrenergic receptors. Catecholamines 17-30 renin Homo sapiens 48-53 14500-9 1976 Normalization of catecholamine-induced enhanced renin release in patients with pheochromocytoma during chronic alpha-adrenergic receptor blockade supports the assumption that (alpha-) adrenergic blocking agents inhibit renin secretion distal to their blockade of specific adrenergic receptors. Catecholamines 17-30 renin Homo sapiens 219-224 1257835-3 1976 It is assumed that the increase in renin is secondary to catecholamine stimulation. Catecholamines 57-70 renin Homo sapiens 35-40 1256000-6 1976 The fact that a correlation was observed in the normal group is compatible with the hypothesis that catecholamines are involved in the regulation of the renin-angiotensin-aldosterone system. Catecholamines 100-114 renin Homo sapiens 153-158 1239966-8 1975 The postoperative increase of plasma renin and consequently plasma aldosterone is possibly a consequence of anaesthetic induced impaired kidney perfusion and/or catecholamine mediated stimulation of renin release. Catecholamines 161-174 renin Homo sapiens 37-42 1239966-8 1975 The postoperative increase of plasma renin and consequently plasma aldosterone is possibly a consequence of anaesthetic induced impaired kidney perfusion and/or catecholamine mediated stimulation of renin release. Catecholamines 161-174 renin Homo sapiens 199-204 6021207-2 1967 Despite concurrent increases in arterial blood pressure, the plasma renin activity of normal subjects increased both in response to the infusion of catecholamines (norepinephrine: epinephrine, 10:1) and in response to stimulation of the sympathetic nervous system by cold. Catecholamines 148-162 renin Homo sapiens 68-73 6021207-6 1967 When orthostatic hypotension was prevented by infusion of catecholamines, however, increases in plasma renin activity and in aldosterone excretion were observed. Catecholamines 58-72 renin Homo sapiens 103-108 1222215-0 1975 Effect of catecholamines on renin release in vitro. Catecholamines 10-24 renin Homo sapiens 28-33 1237420-1 1975 In recent years many investigators have reported the role of the sympathetic nervous system and the catecholamines in the regulation of renin secretion. Catecholamines 100-114 renin Homo sapiens 136-141 1157091-0 1975 [Relation between plasma renin activity and urinary catecholamines in individual types of hypertension (author"s transl)]. Catecholamines 52-66 renin Homo sapiens 25-30 1077779-0 1975 Relationships between plasma renin activity and urinary and plasma catecholamines. Catecholamines 67-81 renin Homo sapiens 29-34 239260-11 1975 The some patients with EH may have a renin-catecholamine relationship and both pressor systems may be linked to be a pathogenic factor for the elevation of blood pressure. Catecholamines 43-56 renin Homo sapiens 37-42 1183075-0 1975 Direct intrarenal action of catecholamines on renin secretion. Catecholamines 28-42 renin Homo sapiens 46-51 4394154-0 1970 Observations on the mechanism of renin release by catecholamines. Catecholamines 50-64 renin Homo sapiens 33-38 32609011-0 2020 Renin and Survival in Patients Given Angiotensin II for Catecholamine-Resistant Vasodilatory Shock. Catecholamines 56-69 renin Homo sapiens 0-5 33280407-12 2021 Further, in correlation matrix analysis, higher 24-hour urinary catecholamines and metanephrines were associated with higher 24-hour urinary aldosterone and plasma renin activity levels in MUCH patients. Catecholamines 64-78 renin Homo sapiens 164-169 28837972-1 2017 Catecholamines stimulate renin-secretion in the juxtaglomerular cells of the kidney and a number of case reports suggest an association between pheochromocytoma and activation of the RAAS. Catecholamines 0-14 renin Homo sapiens 25-30 28837972-2 2017 Therefore, it could be asked whether patients suffering from pheochromocytoma with high concentrations of circulating catecholamines present with oversecretion of renin and aldosterone. Catecholamines 118-132 renin Homo sapiens 163-168 20936939-5 2011 Renin release is acutely increased via the cAMP signaling pathway, which is triggered mainly by catecholamines and other G(s)-coupled agonists, and is inhibited by calcium-related pathways that are commonly activated by vasoconstrictors. Catecholamines 96-110 renin Homo sapiens 0-5 19763821-1 2010 It is now becoming clear that two major systems namely the sympathetic nervous system and the renin-angiotensin system are activated in response to ischemic injury; these result in the elevation of plasma catecholamines and angiotensin II during the development of myocardial infarction as well as congestive heart failure. Catecholamines 205-219 renin Homo sapiens 94-99 15894902-0 2005 Effect of the renin-angiotensin system or calcium channel blockade on the circadian variation of heart rate variability, blood pressure and circulating catecholamines in hypertensive patients. Catecholamines 152-166 renin Homo sapiens 14-19 14722779-8 2004 The increase in plasma volume (PV) that is associated with a tendency for a decrease in plasma active renin is likely to be due to decreased sympathetic activity, and concords with the changes in urinary catecholamine levels during confinement. Catecholamines 204-217 renin Homo sapiens 102-107 25894681-9 2015 The catecholamine VT targeting astroglia can modulate the fundamental functions of astroglia observed in neuroenergetics, in the Glymphatic system, in the central renin-angiotensin system and in the production of long-distance calcium waves. Catecholamines 4-17 renin Homo sapiens 163-168