PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28461340-7 2017 Treatment with BAY 11-7082 or BBG 1 h after CAR injection attenuated pulmonary membrane thickening and polymorphonuclear leukocyte infiltration, reduced NF-kappaB translocation in the nucleus, and inhibited the assembly of the NRLP3/ASC/caspase-1 complex. coomassie Brilliant Blue 30-33 caspase 1 Mus musculus 237-246 28669743-7 2017 These results indicated that inhibition of P2X7R with BBG promoted neuronal survival, not through the activation of survival kinase pathways, but possibly by improved intracellular Ca2+ overload and decreased the levels of Caspase 1, IL-1beta and Bax proteins. coomassie Brilliant Blue 54-57 caspase 1 Mus musculus 223-232 29070142-4 2017 RESULTS: The allo-HSCT aGVHD mouse model was successfully established, the intraperitoneal injection of BBG alleviated the aGVHD clinical manifestations including roachback, ruffled fur, skin peeling and weight loss of recipient mice, decreased P2X7R and IL-1beta expression and reduced the mRNA levels of P2X7R, NLRP3, Caspase-1, IL-1beta and IL-18. coomassie Brilliant Blue 104-107 caspase 1 Mus musculus 320-329 26349656-9 2016 Apyrase, an adenosine triphosphate (ATP) scavenger, or Brilliant Blue G, a purinergic P2X7 receptor antagonist, inhibited the damage as well as caspase-1 activation and IL-1beta processing, despite there being sufficient amounts of pro-IL-1beta and NLRP3. coomassie Brilliant Blue 55-71 caspase 1 Mus musculus 144-153 24022661-8 2013 Blockade of P2X7 activation by BBG suppressed NLRP3/ASC/caspase 1 assembly and the subsequent release of interleukin-1beta (IL-1beta), resulting in a significant reduction in the severity of nephritis and circulating anti-dsDNA antibodies. coomassie Brilliant Blue 31-34 caspase 1 Mus musculus 56-65