PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34208781-9 2021 Additionally, BBG prevents NLRP3 inflammasome activation and consequently the release of active interleukin (IL)-1 and IL-18, involved in the activation of nociceptors. coomassie Brilliant Blue 14-17 NLR family, pyrin domain containing 3 Rattus norvegicus 27-32 34321905-0 2021 The Supportive Role of NSC328382, a P2X7R Antagonist, in Enhancing the Inhibitory Effect of CRID3 on NLRP3 Inflammasome Activation in Rats with Dextran Sodium Sulfate-Induced Colitis. coomassie Brilliant Blue 23-32 NLR family, pyrin domain containing 3 Rattus norvegicus 101-106 33548287-10 2021 However, the combined administration of OLT1177 with BBG potentiated its inhibitory effect on the NLRP3, which was reflected by the additional suppressive effect on caspase-1, IL-1beta, IL-18 levels. coomassie Brilliant Blue 53-56 NLR family, pyrin domain containing 3 Rattus norvegicus 98-103 35202914-4 2022 Coomassie brilliant blue G-250 (CBBG) is proved to be a safe highly selective P2x7R antagonist with promising consequent inactivation of NLRP3 inflammasome. coomassie Brilliant Blue 32-36 NLR family, pyrin domain containing 3 Rattus norvegicus 137-142 35202914-10 2022 The lung protective effects of CBBG might be attributed on the one hand to the inhibition of NLRP3 inflammasome and on the other hand to the inactivation of NF-kappaB. coomassie Brilliant Blue 31-35 NLR family, pyrin domain containing 3 Rattus norvegicus 93-98 33548287-0 2021 BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-kappaB signaling in DSS-induced colitis in rats. coomassie Brilliant Blue 0-3 NLR family, pyrin domain containing 3 Rattus norvegicus 29-34 33548287-0 2021 BBG enhances OLT1177-induced NLRP3 inflammasome inactivation by targeting P2X7R/NLRP3 and MyD88/NF-kappaB signaling in DSS-induced colitis in rats. coomassie Brilliant Blue 0-3 NLR family, pyrin domain containing 3 Rattus norvegicus 80-85 33548287-9 2021 Individual BBG or OLT1177 administration decreased NLRP3 inflammasome recruitment and subsequent activation of caspase-1, IL-1beta, and IL-18. coomassie Brilliant Blue 11-14 NLR family, pyrin domain containing 3 Rattus norvegicus 51-56 32516946-7 2020 Increased IL-2, IL-6, TNFalpha, IL-1beta, IL-18 and overexpression of NLRP3 inflammasome were induced by angiotensin II and suppressed by BBG. coomassie Brilliant Blue 138-141 NLR family, pyrin domain containing 3 Rattus norvegicus 70-75