PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16549198-7 2007 Placental 11beta-HSD2 activity was determined using beclomethasone dipropionate, budesonide, fluticasone propionate, prednisolone, dexamethasone and betamethasone as steroid substrates. Betamethasone 149-162 hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens 10-21 30213491-0 2018 Sex-specific and lasting effects of a single course of antenatal betamethasone treatment on human placental 11beta-HSD2. Betamethasone 65-78 hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens 108-119 30213491-10 2018 RESULTS: In term born females, BET administration was associated with reduced head circumference and decreased 11beta-HSD2 protein levels and enzyme activity. Betamethasone 31-34 hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens 111-122 19535674-2 2009 Antenatal betamethasone alters 11betaHSD2 activity and confers sex-specific advantages in neonatal outcome. Betamethasone 10-23 hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens 31-41 19535674-4 2009 Univariate analyses demonstrated an interaction between timing of betamethasone exposure and sex for 11betaHSD2 activity rate (P = 0.02) and umbilical arterial cortisol (P = 0.01). Betamethasone 66-79 hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens 101-111 19535674-7 2009 For infants born < 72 h after betamethasone exposure, 11betaHSD2 activity was negatively correlated with Clinical Illness Severity Score score (r = -0.79 P = 0.01) and positively correlated with mean arterial blood pressure (r = 0.8 P = 0.01) only in females. Betamethasone 33-46 hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens 57-67 16549198-9 2007 Placental 11beta-HSD2 metabolised beclomethasone, prednisolone, dexamethasone and betamethasone, but not budesonide or fluticasone. Betamethasone 82-95 hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens 10-21 34665470-8 2022 CONCLUSIONS: Data from this study suggest that the presence of two fetoplacental units may increase the betamethasone metabolism by hepatic CYP3A4 and/or placental 11beta-HSD2 enzymes. Betamethasone 104-117 hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens 164-175