PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21224584-1 2010 PURPOSE: The aim of this study was to determine whether the expressions of excision repair cross-complementing-1 (ERCC1) and thymidylate synthase (TS) predict the clinical outcome of patients with esophageal squamous cell carcinoma treated with CDDP/5-FU chemoradiotherapy. cddp 245-249 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 75-112 10741696-6 2000 To determine whether the repair inhibition contributes to the cytotoxic synergism, we examined the effect of the constitutive expression of ERCC1 antisense RNA on the interaction of dFdC and CDDP. cddp 191-195 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 140-145 30668408-15 2019 CONCLUSIONS: We concluded that enhancement of the cytotoxicity to CDDP by coadminstration with DMC was mediated by down-regulation of the expression of TP and ERCC1, regulated by PI3K-Akt-Snail pathway inactivation. cddp 66-70 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 159-164 21224584-1 2010 PURPOSE: The aim of this study was to determine whether the expressions of excision repair cross-complementing-1 (ERCC1) and thymidylate synthase (TS) predict the clinical outcome of patients with esophageal squamous cell carcinoma treated with CDDP/5-FU chemoradiotherapy. cddp 245-249 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 114-119 19381033-6 2009 All ERCC1-negative specimens were sensitive for CDDP in HDRA, and all CDDP-resistant specimens in HDRA showed positive ERCC1 staining. cddp 48-52 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 4-9 21475919-1 2009 Low excision repair cross-complementing 1 (ERCC1) has been associated with a favorable response to cisplatin (CDDP) in several types of malignancies. cddp 110-114 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 4-41 21475919-1 2009 Low excision repair cross-complementing 1 (ERCC1) has been associated with a favorable response to cisplatin (CDDP) in several types of malignancies. cddp 110-114 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 43-48 21475919-2 2009 The present study aimed to investigate whether ERCC1 predicts the response to CDDP-based chemoradiotherapy (CRT) in patients with esophageal squamous cell carcinoma (ESCC) and to evaluate the association between ERCC1 and platinum drug sensitivity in ESCC cell lines. cddp 78-82 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 47-52 21475919-5 2009 Responses to CDDP and oxaliplatin (OXA) in ESCC cell lines were evaluated using the WST-8 colorimetric assay by comparing ERCC1 levels. cddp 13-17 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 122-127 21475919-9 2009 ESCC cell lines with lower ERCC1 showed significantly greater sensitivity to clinically relevant concentrations of CDDP and OXA compared to lines with higher ERCC1 (p<0.01). cddp 115-119 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 27-32 19381033-6 2009 All ERCC1-negative specimens were sensitive for CDDP in HDRA, and all CDDP-resistant specimens in HDRA showed positive ERCC1 staining. cddp 70-74 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 119-124 19381033-7 2009 ERCC1 status was significantly correlated with CDDP sensitivity(p=0.01). cddp 47-51 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 0-5 19381033-9 2009 CONCLUSION: HDRA may provide effective non-platinum adjuvant chemotherapy protocols for patients with ERCC1-positive, i.e. CDDP resistant, NSCLC. cddp 123-127 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 102-107 17353624-10 2007 Expression of ERCC 1, a component of this complex multi-protein system, has been reported to be a determinant of prognosis in CDDP-treated non-small-cell lung cancer patients. cddp 126-130 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 14-20 18751380-13 2008 CONCLUSION: We established a CDDP-resistant cell line using MKN45 cells, in which ERCC1 and GST-pi were increased. cddp 29-33 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 82-87 15720263-5 2005 DNA repair capacity influences response to CDDP and ERCC1 gene stands out as a predictive marker of CDDP sensitivity. cddp 100-104 ERCC excision repair 1, endonuclease non-catalytic subunit Homo sapiens 52-57