PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11836567-15	2002	Although the receptor signaling pathway in apoptosis was not observed by 5-FU, Bax-induced cytochrome c and caspase 3 was also observed in a receptor-independent pathway by 5-FU and CDDP.	cddp	182-186	BCL2 associated X, apoptosis regulator	Homo sapiens	79-82	
15389812-11	2005	The differential induction of p21(WAF1/CIP1) and increase in Bax/Bcl-2 ratios with CDDP and DACH-Ac-Pt in LNCaP-LN3 cells appear to be linked to the relative activity of the two agents against this model.	cddp	83-87	BCL2 associated X, apoptosis regulator	Homo sapiens	61-64	
29887946-16	2018	Relative to the CDDP group, the CDDP+GSH group exhibited 47.92%, 47.82% and 63.75% downregulation in caspase3, caspase9 and bax mRNA expression, respectively, and a 2.17-fold increase in bcl-2 mRNA level.	cddp	32-36	BCL2 associated X, apoptosis regulator	Homo sapiens	124-127	
10493958-5	1999	The introduction of bcl-Xs gene into MKN45 gastric cancer cells increased the sensitivity to VP-16 and taxotere 2-3-fold in the IC50 values, whereas the introduction of bax gene increased the sensitivity to CDDP, VP-16 and taxotere 2-5-fold in the IC50 values, as compared to that of the Neo-transfected MKN45 cells.	cddp	207-211	BCL2 associated X, apoptosis regulator	Homo sapiens	169-172	
30668408-12	2019	Thirdly, DMC treatment markedly increased post-target CDDP resistance pathway including Bax and cytochrome c.	cddp	54-58	BCL2 associated X, apoptosis regulator	Homo sapiens	88-91