PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30668408-12 2019 Thirdly, DMC treatment markedly increased post-target CDDP resistance pathway including Bax and cytochrome c. cddp 54-58 BCL2 associated X, apoptosis regulator Homo sapiens 88-91 29887946-16 2018 Relative to the CDDP group, the CDDP+GSH group exhibited 47.92%, 47.82% and 63.75% downregulation in caspase3, caspase9 and bax mRNA expression, respectively, and a 2.17-fold increase in bcl-2 mRNA level. cddp 32-36 BCL2 associated X, apoptosis regulator Homo sapiens 124-127 10493958-5 1999 The introduction of bcl-Xs gene into MKN45 gastric cancer cells increased the sensitivity to VP-16 and taxotere 2-3-fold in the IC50 values, whereas the introduction of bax gene increased the sensitivity to CDDP, VP-16 and taxotere 2-5-fold in the IC50 values, as compared to that of the Neo-transfected MKN45 cells. cddp 207-211 BCL2 associated X, apoptosis regulator Homo sapiens 169-172 15389812-11 2005 The differential induction of p21(WAF1/CIP1) and increase in Bax/Bcl-2 ratios with CDDP and DACH-Ac-Pt in LNCaP-LN3 cells appear to be linked to the relative activity of the two agents against this model. cddp 83-87 BCL2 associated X, apoptosis regulator Homo sapiens 61-64 11836567-15 2002 Although the receptor signaling pathway in apoptosis was not observed by 5-FU, Bax-induced cytochrome c and caspase 3 was also observed in a receptor-independent pathway by 5-FU and CDDP. cddp 182-186 BCL2 associated X, apoptosis regulator Homo sapiens 79-82