PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22015781-9	2011	Inhibition of mTOR with rapamycin reversed the down-regulation of cellular lipid efflux mediator ABCA1, which resulted from the activation of TLR4 by ligands.	Sirolimus	24-33	ATP binding cassette subfamily A member 1	Homo sapiens	97-102	
17322416-4	2007	The effect of sirolimus on the gene and protein expression of lipoprotein receptors and ATP binding cassettes (ABCA1 and ABCG1) was examined by real-time PCR and Western blotting, respectively.	Sirolimus	14-23	ATP binding cassette subfamily A member 1	Homo sapiens	111-116	
19180880-3	2008	The effects of rapamycin on interleukin-1 beta (IL-1 beta)-induced mRNA and protein changes of low-density lipoprotein receptor (LDLR) and ATP-binding cassette transporter A1 (ABCA1) were assayed by quantitative real-time PCR and Western blot.	Sirolimus	15-24	ATP binding cassette subfamily A member 1	Homo sapiens	139-174	
19180880-3	2008	The effects of rapamycin on interleukin-1 beta (IL-1 beta)-induced mRNA and protein changes of low-density lipoprotein receptor (LDLR) and ATP-binding cassette transporter A1 (ABCA1) were assayed by quantitative real-time PCR and Western blot.	Sirolimus	15-24	ATP binding cassette subfamily A member 1	Homo sapiens	176-181	
19180880-6	2008	Rapamycin dose-dependently suppressed the increased expression of LDLR induced by IL-1 beta and up-regulated the suppressed expression of ABCA1 caused by IL-1 beta.	Sirolimus	0-9	ATP binding cassette subfamily A member 1	Homo sapiens	138-143	
17322416-9	2007	Sirolimus also increased ABCA1 and ABCG1 genes expression, even in the presence of IL-1 beta.	Sirolimus	0-9	ATP binding cassette subfamily A member 1	Homo sapiens	25-30	
15769938-10	2005	Sirolimus overrode the suppression of cholesterol efflux and ABCA1 gene expression induced by the inflammatory cytokine IL-1beta.	Sirolimus	0-9	ATP binding cassette subfamily A member 1	Homo sapiens	61-66