PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25439783-6 2015 RESULTS: The 4E-BP1/eIF4E ratio was adjusted to evaluate the response to rapamycin treatment in TE1 and TE2 esophageal cancer cells. Sirolimus 73-82 N-alpha-acetyltransferase 10, NatA catalytic subunit Homo sapiens 104-107 25439783-7 2015 TE2 cells are sensitized to rapamycin treatment after overexpression of 4E-BP1 or knockdown of eIF4E; TE1 cells become resistant to rapamycin after knockdown of 4E-BP1 or overexpression of eIF4E. Sirolimus 28-37 N-alpha-acetyltransferase 10, NatA catalytic subunit Homo sapiens 0-3 25439783-7 2015 TE2 cells are sensitized to rapamycin treatment after overexpression of 4E-BP1 or knockdown of eIF4E; TE1 cells become resistant to rapamycin after knockdown of 4E-BP1 or overexpression of eIF4E. Sirolimus 132-141 N-alpha-acetyltransferase 10, NatA catalytic subunit Homo sapiens 0-3 25439783-8 2015 These data suggest that the 4E-BP1/eIF4E ratio is a determinant for the response of TE1 and TE2 cells to rapamycin treatment. Sirolimus 105-114 N-alpha-acetyltransferase 10, NatA catalytic subunit Homo sapiens 92-95 25439783-9 2015 Egr-1 expression was higher in TE2 cells compared with other esophageal cancer cell lines, and its knockdown increased 4E-BP1 expression in TE2 cells, which became sensitive to rapamycin treatment. Sirolimus 177-186 N-alpha-acetyltransferase 10, NatA catalytic subunit Homo sapiens 140-143