PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33687217-5	2021	Namely, a citrullinated multiepitope self-antigen (CitP) and rapamycin are incorporated into the nanoemulsions (NEs@CitP/Rapa), which are fabricated by a facial method using commercialized pharmaceutical excipients.	Sirolimus	61-70	transcriptional regulating factor 1	Mus musculus	121-125	
34065421-5	2021	In contrast, rapamycin multiple (M) treatment (Rapa-M-DC) were exposed to 3 treatments over 7 days.	Sirolimus	13-22	transcriptional regulating factor 1	Mus musculus	47-51	
34977433-4	2022	Herein, we design a ROS-responsive targeted micelle system (TT-NM/Rapa) to enhance the delivery efficiency of rapamycin to neurons in AD lesions guided by the fusion peptide TPL, and facilitate its intracellular release via ROS-mediated disassembly of micelles, thereby maximizing autophagic flux modulating efficacy of rapamycin in neurons.	Sirolimus	110-119	transcriptional regulating factor 1	Mus musculus	66-70	
34977433-4	2022	Herein, we design a ROS-responsive targeted micelle system (TT-NM/Rapa) to enhance the delivery efficiency of rapamycin to neurons in AD lesions guided by the fusion peptide TPL, and facilitate its intracellular release via ROS-mediated disassembly of micelles, thereby maximizing autophagic flux modulating efficacy of rapamycin in neurons.	Sirolimus	320-329	transcriptional regulating factor 1	Mus musculus	66-70	
26043934-3	2017	Thus, the aim of the present study was to demonstrate the improved biocompatibility of rapamycin-containing polyethylene glycol (Rapa-PEG)-coating on alginate microcapsules containing xenogeneic islets.	Sirolimus	87-96	transcriptional regulating factor 1	Mus musculus	129-133	
32841911-8	2020	Hence, a combined platform rapamycin encapsulated zeolitic imidazolate frameworks (Rapa@ZIF-8) was constructed and demonstrated a more significant chemo-sensitized effect relative to ZIF-8 nanoparticles or rapamycin treatment alone.	Sirolimus	27-36	transcriptional regulating factor 1	Mus musculus	83-93	
32841911-8	2020	Hence, a combined platform rapamycin encapsulated zeolitic imidazolate frameworks (Rapa@ZIF-8) was constructed and demonstrated a more significant chemo-sensitized effect relative to ZIF-8 nanoparticles or rapamycin treatment alone.	Sirolimus	206-215	transcriptional regulating factor 1	Mus musculus	83-93	
31647755-7	2020	In mice treated with Leuko-Rapa, flow cytometry of disaggregated aortic tissue revealed fewer proliferating macrophages in the aorta (15.6+-9.79 %) compared with untreated mice (30.2+-13.34 %) and rapamycin alone (26.8+-9.87 %).	Sirolimus	197-206	transcriptional regulating factor 1	Mus musculus	27-31	
24850187-2	2014	In this study, male Balb/c mice were divided into three groups: control (n = 12), STZ-induced diabetic (n = 12), and rapamycin-treated diabetic (DM + Rapa) (n = 12), which received intraperitoneal injection of rapamycin (2 mg/kg/48 h) after induction of DM.	Sirolimus	117-126	transcriptional regulating factor 1	Mus musculus	150-154