PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33319976-6 2020 The downregulation of PFKFB4 can help inhibit the SRC3/Akt/mTOR pathway, leading autophagy to the direction of promoting apoptosis of tumor cells, which is induced by the collapse of tumor cellular homeostasis, while low dosages of rapamycin could decrease surgery-induced immune dysfunction. Sirolimus 232-241 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 Homo sapiens 22-28