PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9545305-7 1998 LIF-induced p70 S6 kinase activation, protein synthesis, and c-fos mRNA expression were inhibited by wortmannin and rapamycin. Sirolimus 116-125 LIF interleukin 6 family cytokine Homo sapiens 0-3 25968579-8 2015 Incubation with rapamycin and AZD8055 indicated that mammalian target of rapamycin complex (mTORC)2, but not mTORC1, also is required for LIF-stimulated glucose uptake. Sirolimus 16-25 LIF interleukin 6 family cytokine Homo sapiens 138-141 31479623-7 2020 We further observed that the LIF gene, which is highly induced upon rapamycin treatment, strengthened interactions with up- and down-stream intergenic regions. Sirolimus 68-77 LIF interleukin 6 family cytokine Homo sapiens 29-32 29393372-5 2018 After adding the phosphatidylinositol 3-kinase (PI3K)/AKT signaling inhibitor LY294002 or wortmannin to the LIF differentiation group, LIF-induced changes in the protein expression of TUJ1 and MAP2 were reversed, but this effect could not be prevented by rapamycin, a mechanistic target of rapamycin signaling inhibitor. Sirolimus 255-264 LIF interleukin 6 family cytokine Homo sapiens 135-138 26652669-5 2015 Rapamycin treatment induced the upregulation of cytokine genes, including those from the Interleukin (IL)-6 signaling network, such as IL-8 and the Leukemia Inhibitory Factor (LIF), while quiescent fibroblasts demonstrated up-regulation of genes involved in the complement and coagulation cascade. Sirolimus 0-9 LIF interleukin 6 family cytokine Homo sapiens 148-174 26652669-5 2015 Rapamycin treatment induced the upregulation of cytokine genes, including those from the Interleukin (IL)-6 signaling network, such as IL-8 and the Leukemia Inhibitory Factor (LIF), while quiescent fibroblasts demonstrated up-regulation of genes involved in the complement and coagulation cascade. Sirolimus 0-9 LIF interleukin 6 family cytokine Homo sapiens 176-179