PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20348217-3	2010	In this study we hypothesized that sirolimus inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGR)-mediated cholesterol synthesis in human vascular smooth muscle cells (VSMCs) under inflammatory stress.	Sirolimus	35-44	high mobility group AT-hook 1	Homo sapiens	103-107	
20348217-5	2010	Further studies showed that sirolimus inhibited both the HMGR gene and protein expression in VSMCs treated with or without IL-1beta.	Sirolimus	28-37	high mobility group AT-hook 1	Homo sapiens	57-61	
20348217-10	2010	In conclusion, sirolimus inhibits cholesterol synthesis induced by inflammatory stress through the downregulation of HMGR expression and the acceleration of HMGR protein degradation.	Sirolimus	15-24	high mobility group AT-hook 1	Homo sapiens	117-121	
20348217-10	2010	In conclusion, sirolimus inhibits cholesterol synthesis induced by inflammatory stress through the downregulation of HMGR expression and the acceleration of HMGR protein degradation.	Sirolimus	15-24	high mobility group AT-hook 1	Homo sapiens	157-161	
7559428-0	1995	Interleukin 4-inducible phosphorylation of HMG-I(Y) is inhibited by rapamycin.	Sirolimus	68-77	high mobility group AT-hook 1	Homo sapiens	43-51