PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
24345797-7	2014	Furthermore, pretreatment of HK-2 cells with rapamycin reduced the production of LCN2/NGAL and HAVCR1/KIM-1 and the level of apoptosis induced by urinary proteins.	Sirolimus	45-54	hepatitis A virus cellular receptor 1	Homo sapiens	95-101	
33748286-6	2021	Furthermore, rapamycin reduced urinary protein-induced NGAL and KIM-1 secretion and cell growth inhibition, while chloroquine played the opposite effect, indicating that autophagy activation by ERK pathway was an adaptive response in the exposure to urinary proteins.	Sirolimus	13-22	hepatitis A virus cellular receptor 1	Homo sapiens	64-69	
29556265-8	2018	The present study also demonstrated that the activation of autophagy with rapamycin led to an improvement in the AOPP-induced overexpression of kidney injury molecule 1 and neutrophil gelatinase-associated lipocalin, two biomarkers of RTEC injury, whereas inhibiting autophagy with chloroquine further increased their expression during AOPP treatment.	Sirolimus	74-83	hepatitis A virus cellular receptor 1	Homo sapiens	144-168	
26538632-7	2016	Kim-1 expression led to activation of the mammalian target of rapamycin (mTOR) pathway, and inhibition of this pathway with rapamycin increased survival.	Sirolimus	62-71	hepatitis A virus cellular receptor 1	Homo sapiens	0-5	
24345797-7	2014	Furthermore, pretreatment of HK-2 cells with rapamycin reduced the production of LCN2/NGAL and HAVCR1/KIM-1 and the level of apoptosis induced by urinary proteins.	Sirolimus	45-54	hepatitis A virus cellular receptor 1	Homo sapiens	102-107