PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
31534138-8	2019	Combinatorial use of CtBP inhibitors with the LSD1 inhibitor pargyline has synergistic influence.	Pargyline	61-70	lysine demethylase 1A	Homo sapiens	46-50	
34908406-0	2021	Installation of Pargyline, a LSD1 Inhibitor, in the HDAC Inhibitory Template Culminated in the Identification of a Tractable Antiprostate Cancer Agent.	Pargyline	16-25	lysine demethylase 1A	Homo sapiens	29-33	
34908406-1	2021	Pragmatic insertion of pargyline, a LSD1 inhibitor, as a surface recognition part in the HDAC inhibitory pharmacophore was planned in pursuit of furnishing potent antiprostate cancer agents.	Pargyline	23-32	lysine demethylase 1A	Homo sapiens	36-40	
24886859-10	2014	Treatment with tranylcypromine and pargyline, which are potent inhibitors of LSD1, prevented IL-1beta-induced H3K9 demethylation at the mPGES-1 promoter and expression of mPGES-1.	Pargyline	35-44	lysine demethylase 1A	Homo sapiens	77-81	
26872725-6	2016	Moreover, treatments of LSD1 chemical inhibitors (pargyline and tranylcypromine) induced its protein reduction probably via enhanced protein degradation and produced similar phenotypic changes resembling LSD1 silencing in OSCC cells.	Pargyline	50-59	lysine demethylase 1A	Homo sapiens	24-28	
26872725-6	2016	Moreover, treatments of LSD1 chemical inhibitors (pargyline and tranylcypromine) induced its protein reduction probably via enhanced protein degradation and produced similar phenotypic changes resembling LSD1 silencing in OSCC cells.	Pargyline	50-59	lysine demethylase 1A	Homo sapiens	204-208	
26435505-0	2015	Inhibition of LSD1 by Pargyline inhibited process of EMT and delayed progression of prostate cancer in vivo.	Pargyline	22-31	lysine demethylase 1A	Homo sapiens	14-18	
26435505-4	2015	This study examined the effect of Pargyline (an inhibitor of LSD1) on the process of EMT in vitro and in vivo.	Pargyline	34-43	lysine demethylase 1A	Homo sapiens	61-65	
28377178-4	2017	As such, KDM1A inhibitors, such as pargyline and GSK2879552, dramatically suppress stem-like properties of sorafenib-resistant HCC cells.	Pargyline	35-44	lysine demethylase 1A	Homo sapiens	9-14	
28058134-3	2016	Here, we investigated pargyline, an inhibitor of lysine-specific demethylase 1 (LSD1), which mainly catalyzes the demethylation of the di- and mono-methylation of H3K4.	Pargyline	22-31	lysine demethylase 1A	Homo sapiens	49-78	
28058134-3	2016	Here, we investigated pargyline, an inhibitor of lysine-specific demethylase 1 (LSD1), which mainly catalyzes the demethylation of the di- and mono-methylation of H3K4.	Pargyline	22-31	lysine demethylase 1A	Homo sapiens	80-84	
25627913-3	2015	Furthermore, LNCap cell line was treated with Pargyline (an inhibitor of LSD1), and Western blot was used to analyze LSD1 and E-cadherin expression.	Pargyline	46-55	lysine demethylase 1A	Homo sapiens	73-77	
25627913-9	2015	Moreover, Pargyline inhibited activity of LSD1 and up-regulated E-cadherin expression.	Pargyline	10-19	lysine demethylase 1A	Homo sapiens	42-46	
21452019-4	2012	We also demonstrated that inhibition of LSD1 activity by a pharmacological inhibitor, pargyline, or siRNA resulted in increased acetylation of H3K9 (AcH3K9).	Pargyline	86-95	lysine demethylase 1A	Homo sapiens	40-44	
24165091-13	2013	Chemical LSD1 inhibition induced cytotoxicity in ovarian cancer lines, which roughly correlated with their reported LSD1 inhibitory potential (RN-1,S2101 >> pargyline,TCP).	Pargyline	163-172	lysine demethylase 1A	Homo sapiens	9-13	
22036763-3	2011	In this study, we found that Sp1 could be methylated and that methylation was maintained by treatment with pargyline, a lysine-specific demethylase 1 (LSD1) inhibitor or knock LSD1 down directly.	Pargyline	107-116	lysine demethylase 1A	Homo sapiens	120-149	
22493729-11	2012	Interruption of LSD1 using siRNA or a chemical inhibitor, pargyline, suppressed proliferation, migration and invasion of A549, H460 and 293T cells.	Pargyline	58-67	lysine demethylase 1A	Homo sapiens	16-20	
22036763-3	2011	In this study, we found that Sp1 could be methylated and that methylation was maintained by treatment with pargyline, a lysine-specific demethylase 1 (LSD1) inhibitor or knock LSD1 down directly.	Pargyline	107-116	lysine demethylase 1A	Homo sapiens	151-155	
16079795-8	2005	Furthermore, we identify pargyline as an inhibitor of LSD1.	Pargyline	25-34	lysine demethylase 1A	Homo sapiens	54-58