PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25998443-5 2015 METHODS: The effect of ambroxol and/or beclomethasone dipropionate on IL-8, RANTES and iNOS levels was assessed by Western blot analysis; IL-8, MPO and 3-NT levels were measured by ELISA. Beclomethasone 39-66 C-X-C motif chemokine ligand 8 Homo sapiens 70-74 25998443-9 2015 Beclomethasone dipropionate had no effect on RANTES but halved iNOS expression and IL-8 release. Beclomethasone 0-27 C-X-C motif chemokine ligand 8 Homo sapiens 83-87 25998443-11 2015 Ambroxol and beclomethasone dipropionate inhibited LPS-stimulated IL-8, MPO and 3-NT release (p < 0.05). Beclomethasone 13-40 C-X-C motif chemokine ligand 8 Homo sapiens 66-70 25998443-12 2015 Ambroxol/beclomethasone dipropionate combination potentiated the inhibition of IL-8 and 3-NT production in BEAS-2B with PMNs (p < 0.05 and p < 0.01, respectively). Beclomethasone 9-36 C-X-C motif chemokine ligand 8 Homo sapiens 79-89 25998443-14 2015 CONCLUSION: The additive effect of ambroxol and beclomethasone dipropionate on IL-8 and 3-NT inhibition suggests new therapeutic options in the treatment of neutrophil-related respiratory diseases such as chronic obstructive pulmonary disease and respiratory infections. Beclomethasone 48-75 C-X-C motif chemokine ligand 8 Homo sapiens 79-89 14643170-5 2004 Pre-treatment with beclomethasone, budesonide or fluticasone reduced TNFalpha- and IL-1beta-stimulated IL-8 and RANTES release from HASMC in a dose dependent manner. Beclomethasone 19-33 C-X-C motif chemokine ligand 8 Homo sapiens 103-107 15679717-4 2005 RESULTS: The release of GM-CSF, RANTES and IL-8 in ISC was significantly reduced by BDP plus salbutamol or formoterol as compared with either drug alone (P < 0.0001). Beclomethasone 84-87 C-X-C motif chemokine ligand 8 Homo sapiens 43-47 14643170-8 2004 The results suggest that the topical steroids fluticasone, budesonide and to a lesser extent beclomethasone may have beneficial effects on airway inflammation in asthma by reducing RANTES and IL-8-induced leukocyte infiltration into the airway wall. Beclomethasone 93-107 C-X-C motif chemokine ligand 8 Homo sapiens 192-196 14643170-2 2004 This study was performed to investigate the effectiveness of the commonly used steroids beclomethasone, budesonide and fluticasone in downregulating HASMC production of RANTES and IL-8. Beclomethasone 88-102 C-X-C motif chemokine ligand 8 Homo sapiens 180-184 7798535-7 1994 Treatment with inhaled beclomethasone dipropionate 500 micrograms twice a day led to a significant decrease in both the expression of GM-CSF (p < 0.01) and IL-8 (p < 0.02) and the number of EG2-staining cells (p < 0.01) in the epithelium. Beclomethasone 23-50 C-X-C motif chemokine ligand 8 Homo sapiens 159-163 7542097-0 1995 Expression of granulocyte/macrophage-colony-stimulating factor, interleukin-8 and RANTES in the bronchial epithelium of mild asthmatics is down-regulated by inhaled beclomethasone dipropionate. Beclomethasone 165-192 C-X-C motif chemokine ligand 8 Homo sapiens 64-77 11015126-0 2000 Effects of early inhaled beclomethasone therapy on tracheal aspirate inflammatory mediators IL-8 and IL-1ra in ventilated preterm infants at risk for bronchopulmonary dysplasia. Beclomethasone 25-39 C-X-C motif chemokine ligand 8 Homo sapiens 92-96 11015126-7 2000 Median IL-8 levels were lower in beclomethasone versus placebo infants on study days 8 (82.9 vs. 209.2, P < 0.01) and 15 (37.4 vs. 77.4, P < 0.03) after controlling for antenatal glucocorticoid therapy and maternal race. Beclomethasone 33-47 C-X-C motif chemokine ligand 8 Homo sapiens 7-11 11015126-9 2000 Fewer beclomethasone infants with baseline IL-8 levels in the interquartile range required systemic glucocorticoid therapy (beclomethasone 30.6% vs. placebo 65.8%, P < 0.01) or developed BPD (beclomethasone 42.4% vs. placebo 69.4%, P < 0.03). Beclomethasone 6-20 C-X-C motif chemokine ligand 8 Homo sapiens 43-47 11015126-11 2000 Beclomethasone-treated infants with moderately elevated baseline IL-8 levels received less subsequent systemic glucocorticoid therapy and had a lower incidence of BPD than nontreated infants. Beclomethasone 0-14 C-X-C motif chemokine ligand 8 Homo sapiens 65-69 7798535-10 1994 Also, beclomethasone dipropionate may inhibit eosinophil activation partly by downregulating the expression of GM-CSF and IL-8 in the bronchial epithelium. Beclomethasone 6-33 C-X-C motif chemokine ligand 8 Homo sapiens 122-126